Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN1987 Macrophylline
1. Macrophylline A shows weak inhibitory action on KCl-induced contraction.
BCN1995 Indicine
1. Indicine N-oxide is a more active antitumor agent than its free base Indicine.
BCN1996 Indicine N-oxide
1. Indicine N-oxide, a pyrrolizidine alkaloid present in the plant Heliotropium indicum, shows promising cytotoxic activity in various tumor models that due to its DNA damaging effects and depolymerization of microtubules.
BCN1997 Intermedine
1. Intermedin (IMD), a multi-functional peptide, plays important roles in cardiovascular protection, the endogenous IMD and its receptor complexes are induced in hypertrophic cardiomyocytes and proposed to play an important role in the pathogenesis of cardiac hypertrophy. 2. Intermedin can decrease the melanin content of the skin of Rana pipiens.
BCN1998 7-Acetylintermedine
1.7-Acetylintermedine, 7-acetyllycopsamine, and symlandine are pyrrolizidine alkaloids, isolated from comfrey, can produce hepatotoxicity in livestock and humans and carcinogenicity in experimental animals.
BCN2000 7-Acetyllycopsamine
1. 7-Acetyllycopsamine, 7-acetylintermedine, and symlandine are pyrrolizidine alkaloids, isolated from comfrey, can produce hepatotoxicity in livestock and humans and carcinogenicity in experimental animals. 2. 7-Acetyllycopsamine exhibits antibacterial effects with a MIC of 1.7 mg/ml in E. coli.
BCN2001 Lasiocarpine
1. Lasiocarpine can produce liver damage. 2. Lasiocarpine has antimitotic action. 3. Lasiocarpine has hepatocarcinogenicity, the effect can be better explained by its strong selection (promotion) influence on initiated hepatocytes, rather than by its very weak initiating activity.
BCN2002 Lasiocarpine N-oxide
1. Lasiocarpine-N-oxide shows antimicrobial activity against selected pathogenic bacteria and fungi.