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BCN5552/480-20-6 |
Aromadendrin
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Aromadendrin, a flavonol, has been reported to possess a variety of pharmacological activities such as anti-inflammatory, antioxidant, and anti-diabetic properties, it exhibits anti-inflammatory activity through the suppression of nuclear translocation of NF-κB and phosphorylation of...
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BCN5565/481-72-1 |
Aloeemodin
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Aloeemodin is able to interact with DNA under certain in vitro conditions, however, in vivo it is negative did not indicate a genotoxic potential, thus, it may be assumed that a genotoxic risk for man might be unlikely.[1]
Aloeemodin has inhibition of β-amyloid aggregation, and has...
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BCN5566/481-73-2 |
Citreorosein
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Citreorosein, a naturally occurring anthraquinone derivative isolated from Polygoni cuspidati radix, attenuates cyclooxygenase-2-dependent prostaglandin D2 generation by blocking Akt and JNK pathways in mouse bone marrow-derived mast cells, it represents a potential therapeutic approa...
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BCN5567/481-74-3 |
Chrysophanol
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Chrysophanol has anti-inflammatory activity through the suppression of NF-κB/caspase-1 activation in vitro and in vivo.[1]
Chrysophanol induces necrosis through the production of ROS and alteration of ATP levels in J5 human liver cancer cells.[2]
Chrysophanol has mild cytotoxicity an...
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BCN5573/482-39-3 |
Afzelin
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Afzelin, isolated from Cornus macrophylla, has antibacterial effects on Pseudomonas aeruginosa, its minimum inhibitory concentration (MIC) is 31 µg/mL.[1]
Afzelin has several cellular activities such as DNA-protective, antioxidant, and anti-inflammatory as well as UV-absorbing acti...
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BCN5574/482-44-0 |
Imperatorin
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Imperatorin, a biologically active furanocoumarin from the roots of Angelica dahurica (Umbelliferae), can induce apoptosis in human promyelocytic leukaemia, HL-60 cells,
and induces apoptosis was significantly blocked by Z-VAD-FMK (a broad spectrum caspase inhibitor), Z-LEHD-FMK (a ca...
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BCN5579/483-66-9 |
Sphondin
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Sphondin, a furanocoumarin derivative isolated from Heracleum laciniatum, possesses an inhibitory effect on IL-1beta-induced increase in the level of COX-2 protein and PGE(2) release in A549 cells, the inhibitory mechanism, at least in part, through suppression of NF-kappaB activity,Â...
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BCN5581/484-12-8 |
Osthol
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Osthol, one major component of cnidii monnieri fructus, has anti-allergic effect.[1]
Osthol can inhibit P-388 D1 cells in vivo and induce apoptosis in HeLa cells in vitro in a time- and concentration-dependent manner, and that osthol is good lead compound for developing antitumor drug...
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