Products with Wound-healing bioactivity

Cat.No. Product Name
BCN3671 Loureirin A
Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling. Loureirin A activates Wnt/-catenin pathway and promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound.The molecular mechanism of Loureirin A and Wnt signaling pathway mediated anti- hepatic fibrosis and anti- angiogenesis may involve down- regulation the expression of Frizzled- 4,inhibiting the synthesis and secretion of α- SMA,TGF- β1and the proliferation of HSCs.
BCN4094 Darutoside
Darutoside can improve skin elasticity, surface appearance and stretch mark removal, through soothing the skin, decreasing inflammation, restoring collagen and promoting collagen production; it could as an appropriate treatment for wounds.
BCN4280 Specioside
1. Specioside has analgesic activity. 2. Specioside has anti-dyspeptic and astringent activities. 3. Specioside has liver stimulating and wound healing activities. 4. Specioside exhibits potent antioxidant activity. 5. Specioside ameliorates oxidative stress and promotes longevity in Caenorhabditis elegans.
BCN4306 (-)-Usnic acid
Usnic acid has antitumoral, acaricidal, larvicidal, antiviral, antibiotic, antipyretic, analgesic,gastroprotective, antioxidative and anti-inflammatory activities. Use of reconstituted bovine type-I collagen-based films containing usnic acid can improve burn healing process in rats. Usnic acid perturbs various interrelated signaling pathways and that autophagy induction is a defensive mechanism against usnic acid-induced cytotoxicity; it disturbs calcium homeostasis, induces ER stress, and that Usnic acid-induced cellular damage occurs at least partially via activation of the Ca(2+) channel of SOCE.
BCN4655 Deoxyelephantopin
1. Deoxyelephantopin has hepatoprotective activity. 2. Deoxyelephantopin has wound healing activity. 3. Deoxyelephantopin has anti-inflammatory activity. 4. Deoxyelephantopin has antitumor activity, by inhibiting metastatic, inducing apoptosis, modulating oxidative stress , STAT3/p53/p21 signaling, MAPK pathway, PI3k/Akt/mTOR pathway, caspase cascades, and ROS .

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