Products with Neuroprotection Bioactivity

Explore BioCrick products associated with Neuroprotection biological activity, including catalog numbers, product names and available bioactivity information.

Neuroprotection Bioactivity Products

Cat. No. Product Name
BCN1684 Rutin
Rutin has antioxidant, anti-inflammatory, anti-allergic, gastroprotective, anticonvulsant, anti-angiogenic and antiviral properties, it may protect against spatial memory impairment induced by trimethyltin. Rutin exerts anti-inflammatory effects in UVB-irradiated mouse skin by inhibiting expression of COX-2 and iNOS, which is attributable to its suppression of p38 MAP kinase and JNK signaling responsible for AP-1 activation.
BCN1929 Cochlearine
1. Cochlearines A can significantly inhibit Cav3.1 T-type calcium channel (TTCC) and show noticeable selectivity against Cav1.2, Cav2.1, Cav2.2, and Kv11.1 (hERG) channels; and TTCC inhibitors hold great potential for the treatment of a variety of neurological disorders.
BCN1945 Tigloidine
1.Tigloidine hydrobromide, a naturally occuring analogue of atropine, could be as a substitute for atropine in the treatment of parkinsonism.
BCN2080 Emiline
1. (±)-Emiline displays good neuroprotective effect against the corticosterone-induced apoptosis in PC12 cells.
BCN2167 Fingolimod hydrochloride
Fingolimod hydrochloride is an oral sphingosine-1-phosphate analogue that was approved by the FDA in 2010 for the treatment of relapsing forms of multiple sclerosis (MS). Fingolimod hydrochloride , a pak1 activator, can inhibit astemizole-induced hypertrophy and cytotoxicity in H9c2 cells, suggests that antihistamine-induced cardiac adverse effects are associated with pak1 expression and function.The gels containing 0.50% fingolimod hydrochloride (FNGL) and FNGL 0.50% plus 6% colloidal oatmeal have potential for the treatment of atopic dermatitis (AD).

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