Products with Neuroprotection bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2744 | Sarcosine |
| Sarcosine is a competitive inhibitor of the type I glycine transporter (GlyT1) and an N-methyl-D-aspartate receptor (NMDAR) co-agonist, it preconditioning induces ischemic tolerance against global cerebral ischemia and this neuroprotective state is associated with changes in glycine transport and reduction of NR2B-containing NMDAR expression.Sarcosine modulates endothelial cell function relevant to angiogenesis through modulation of PI3K/Akt/mTOR pathway. | |
| BCN2756 | Hirsuteine |
| Hirsuteine exhibits potent neuroprotective effects against glutamate-induced HT22 cell death. Hirsuteine non-competitively antagonizes nicotine-evoked dopamine release by blocking ion permeation through nicotinic receptor channel complexes. | |
| BCN2758 | Hirsutine |
| Hirsutine has anticancer, cardioprotective, anti‑hypertensive and anti-arrhythmic activities, it also has vasodilatation activity, the mechanism is related to blockade of Ca2+ influx through L-type Ca2+ channels and inhibition of intracellular Ca2+ release may have no relationship with K+ channels. Hirsutine reduces the production of various neurotoxic factors in activated microglial cells and possesses neuroprotective activity in a model of inflammation-induced neurotoxicity. | |
| BCN2762 | Swertisin |
| Swertisin, a novel herbal biomolecule, shows a strong antihyperglycemic action, it provides low cost and readily available differentiating agent that can be translated as a therapeutic tool for effective treatment in diabetes. | |
| BCN2825 | Officinalisinin I |
| 1. Officinalisinin Ⅰ can effectively reduce the blood glucose and protect nerve injuryin diabetic mice. | |
