Products with Hemostasis bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2710 | Tranexamic acid |
| Tranexamic acid is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM. Tranexamic acid appears to be a promising drug for the prevention and treatment of PPH after both vaginal and caesarean delivery, it can reduce mortality due to traumatic bleeding by a third, without apparent safety issues. | |
| BCN2842 | Buddlejasaponin IVb |
| Buddlejasaponin IVb(200 uM) can shorten thrombin time (TT) by 20.6 %, suggests that it has hemostasis efficacy. | |
| BCN2942 | Zingiberen newsaponin |
| 1. Zingiberensis newsaponin I exhibits induction effect on platelet aggregation. 2. Zingiberensis saponin can inhibit the proliferation of a panel of established human and murine cancer cell lines in vitro, its proliferation inhibitory effect is associated with its apoptosis-inducing effect by activation of caspase-3 and caspase-9 and specific proteolytic cleavage of poly (ADP-ribose) polymerase, thus, zingiberensis saponin is an effective natural agent for cancer therapy. | |
| BCN5291 | Ziyuglycoside II |
| Ziyuglycoside II has a wide range of clinical applications including hemostasis, antibiosis, anti-inflammation and anti-oxidation. Ziyuglycoside II has inhibitory effect on the growth of MDA-MB-435 cells, it induces cell cycle arrest and apoptosis through activation of ROS/JNK pathway in human breast cancer cells.Ziyuglycoside II methyl ester possess improved anti-diabetic properties, and has hepato-renal protective activities in type 2 diabetes. | |
| BCN5332 | Stachydrine hydrochloride |
| Stachydrine hydrochloride promotes the protein expression of IL-12 and IL-6, as well as the mRNA expression of T-bet and RORγt, while inhibiting the mRNA expression of GATA-3 and Foxp3; the Th1/Th2/Th17/Treg paradigm induced by Stachydrine hydrochloride contributed to the reduction in uterine bleeding in RU486-induced abortion mice. | |
