Products with Antioxidants bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN6208 | Cannabidiol |
| Cannabidiol has a potent anti-arthritic effect in collagen-induced arthritis through its combined immunosuppressive and anti-inflammatory actions, it has a pharmacological profile similar to that of atypical antipsychotic drugs. Cannabidiol exerts a combination of neuroprotective, anti-oxidative and anti-apoptotic effects against beta-amyloid peptide toxicity, and that inhibition of caspase 3 appearance from its inactive precursor, pro-caspase 3, by cannabidiol is involved in the signalling pathway for this neuroprotection. Cannabidiol may have great therapeutic potential in the treatment of diabetic complications, and perhaps other cardiovascular disorders, by attenuating oxidative/ nitrative stress, inflammation, cell death and fibrosis. | |
| BCN6214 | 3,4-Dihydroxybenzaldehyde |
| 3,4-Dihydroxybenzaldehyde, a potent tyrosinase inhibitor, has antifungal activity, it can inhibit oxidative DNA damage and apoptosis via its antioxidant activity. It inhibits the phosphotransferase activity of CKII with IC(50) of about 783 microM, it may function by inhibiting oncogenic disease, at least in part, through the inhibition of CKII activity. It inhibits the H2O2-induced apoptosis of granulosa cells, promotes estradiol secretion in granulosa cells and enhanced the mRNA expression levels of steroidogenic factor 1, a promoter of key steroidogenic enzymes. | |
| BCN6217 | Cinnamic acid |
| Cinnamic acid, a naturally occurring aromatic fatty acid of low toxicity, has anti-diabetic , anticancer and antioxidant activities. It is a cell differentiation inducer and protein isoprenylation inhibitor, shows a significant radio-protective effect by reducing the DNA damage induced by X-rays. Cinnamic acid inhibited feeding by detritivores, this inhibition occurs at concentrations found in nature and may be a major factor controlling the rate of decay of organic matter. It inhibited mushroom tyrosinase activity in reversiblywith the IC 50 value of 2.10 mM. | |
| BCN6222 | Ergosterol peroxide glucoside |
| 1. Ergosterol peroxide exhibits inhibitory effects on human breast adenocarcinoma MCF-7 cells, it inhibits the growth of MCF-7 cells by inducing cell apoptosis. 2. Ergosterol peroxide exhibits hACAT-1 and Lp-PLA2 inhibitory effects, with inhibitory values of 51.6 +/- 0.9 and 51.7 +/- 1.2%, at a treatment concentration of 0.23 mM; suggests that it could as an anti-atherosclerosis agent. 3. Ergosterol peroxide shows very strong anticomplementary activity on the classical pathway, the IC(50) values being 5.0 muM. 4. Ergosterol peroxide can suppress inflammatory responses in RAW264.7 macrophages and growth of HT29 colon adenocarcinoma cells, it appears to suppress cell growth and STAT1 mediated inflammatory responses by altering the redox state in HT29 cells. 5. Ergosterol peroxide has anti-melanogenic activity. 6. Ergosterol peroxide has amoebicidal activity (IC50 =4.23nM), it produces a strong cytotoxic effect against amoebic growth. 7. Ergosterol peroxide has osteoclastogenesis inhibitory effect, it shows an inhibitory effect in a dose-dependent manner and an inhibition rate of up to 62% with low cytotoxicity, even at a concentration as low as 1.0 microg/mL. 8. Ergosterol peroxide has antibacterial activity against Mycobacterium tuberculosis and has antiviral action. 9. Ergosterol peroxide has anti-oxdiant activity. | |
| BCN6244 | 2,24-Dihydroxyursolic acid |
| 1. 2,24-Dihydroxyursolic acid shows DPPH free radical scavenging and superoxide anion scavenging activity. | |
