Products with Anticancer bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5381 | Beta-Hederin |
| 1. Beta-Hederin has antileishmanial activity. 2. Beta-Hederin has apoptotic effect on breast cancer cells, it could be a promising candidate for chemotherapy of breast cancer. | |
| BCN5388 | Luteolin-7-O-glucoside |
| Luteolin-7-O-glucoside has cardioprotective, anti-asthmatic, anticancer, anti-inflammatory, and antioxidative activities, it can suppress leukotriene C(4) production and degranulation by inhibiting the phosphorylation of mitogen activated protein kinases and phospholipase Cγ1 in activated mouse bone marrow-derived mast cells.Luteolin-7-O-glucoside modulated the Nrf2/MAPK/ PTEN/Akt /ERK/AP-1/PI3K-Akt signaling pathways, it suppressed the expression of β-catenin. | |
| BCN5389 | Cordycepin |
| Cordycepin possesses immunological stimulating,anti-hyperglycemia, anti-cancer, neuroprotective, antifungal, antibacterial, anti-inflammatory, anti-virus and anti-infection activities. Cordycepin has inhibitory effects on osteoclast differentiation in vitro and that it suppresses inflammatory bone loss in vivo. Cordycepin inhibited the production of NO production by down-regulation of iNOS and COX-2 gene expression via the suppression of NF-κB activation, Akt and p38 phosphorylation, suppressed HMGA2, Twist1 and ZEB1-dependent melanoma invasion and metastasis by targeting miR-33b. | |
| BCN5393 | Cepharanthine |
| Cepharanthine has anti-plasmodial, anti-tumor , anti-inflammatory, antiallergic, antioxidant, and immunomodulatory activities in vivo, and it is a highly potent inhibitor of HIV-1 replication in a chronically infected monocytic cell line. Cepharanthine inhibits the HIV-1 entry process by reducing plasma membrane fluidity, and the plasma membrane is therefore an identical target to prevent viral infection. | |
| BCN5401 | Arenobufagin |
| Arenobufagin is a potent Na + /K + pump inhibitor, and is also a specific inhibitor of VEGF-mediated angiogenesis. Arenobufagin has antineoplastic effect that involves cross talk between apoptosis and autophagy via inhibition of the PI3K/Akt/mTOR pathway. | |
