Products with Anticancer bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5557 | Chrysin |
| Chrysin, a naturally-occurring ligand for benzodiazepine receptors, with anticonvulsant , anti-inflammation, anti-cancer, hepatoprotective, and anti-oxidation properties. Chrysin induced apoptosis is mediated through caspase activation and Akt inactivation in U937 leukemia cells; it prevented the development of DN in HFD/STZ-induced type 2 diabetic rats through anti-inflammatory effects in the kidney by specifically targeting the TNF-α pathway. | |
| BCN5558 | Naringenin |
| Naringenin is a weak estrogen that also exhibits partial antiestrogenic activity in the female rat uterus and MCF-7 human breast cancer cells. Naringenin is also a agent for the treatment of hepatitis C virus (HCV) infection. Naringenin has hypocholesterolemic, antioxidant, free radical scavenger, anti-cancer, anti-inflammatory, neuroprotective, carbohydrate metabolism promoter, and immune system modulator properties. Naringenin possesses potent antidepressant-like property via the central serotonergic and noradrenergic systems. | |
| BCN5560 | Acacetin |
| Acacetin is an atrium-selective agent that prolongs the atrial effective refractory period without prolonging the corrected QT interval and effectively prevents atrial fibrillation (AF) in anesthetized dogs after intraduodenal administration. Acacetin has anti-cancer, anti-mutagenic, spasmolytic and antinociceptive, anti-inflammatory and anti-peroxidative effects. | |
| BCN5562 | Lecanoric acid |
| 1. Lecanoric acid analogues antagonizes several enzymic and cellular effects of the tumour promoter. 2. Lecanoric acid analogues inhibits prostaglandin synthetase and delayed-type hypersensitivity responses against sheep red blood cells in mice. 3. Lecanoric acid shows antioxidant activity with an IC50 value of 79-95 ug/ml, it at 100 ug/ml conc. shows high growth stimulating activity in terms of increased dry matter of biomass (56.08 mg) of L. casei. | |
| BCN5565 | Aloeemodin |
| Aloeemodin is an interferon-inducing agent with IC50 of about 1 μg/mL for JEV and of about 0.33 μg/mL for EV71. Aloeemodin has antitumor, neuroprotective, and anti-fibrosis effects, it inhibited β-amyloid aggregation, downregulated the expression of Smad2 mRNA and TGF-β1,TIMP1,and type Ⅰ and Ⅲ collagen proteins,and upregulated the expression of Smad7 mRNA. | |
