Allergy Research

Allergy is a hypersensitivity disorder characterized by an exaggerated immunologic response to an otherwise innocuous agent, called an allergen. Allergies can be caused by both host (race, gender, hereditary) and environmental factors (pollution, diet, infection).

Allergy Research Products Targets

Products for Allergy Research - Page 3

  1. Cat.No. Product Name Information/Activity
  2. BCN2192 Hydrocortisone Hydrocortisone is a steroid hormone or glucocorticoid produced by the adrenal gland. Hydrocortisone chemical structure
  3. BCC4530 Histamine 2HCl Histamine dihydrochloride is an endogenous metabolite. Histamine 2HCl chemical structure
  4. BCC6736 HTMT dimaleate 195867-54-0 HTMT dimaleate chemical structure
  5. BCC7379 2-Pyridylethylamine dihydrochloride 3343-39-3 2-Pyridylethylamine dihydrochloride chemical structure
  6. BCC7691 Astemizole Astemizole (R 43512), a second-generation antihistamine drug to diminish allergic symptoms with a long duration of action, is a histamine H1-receptor antagonist, with an IC50 of 4 nM. Astemizole also shows potent hERG K+ channel blocking activity with an IC50 of 0.9 nM. Astemizole has antipruritic effects. Astemizole chemical structure
  7. BCC4517 Cetirizine DiHCl Cetirizine dihydrochloride, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine dihydrochloride marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3]. Cetirizine DiHCl chemical structure
  8. BCC4528 Clemastine Fumarate Clemastine (fumarate) (HS-592 (fumarate)) is a selective histamine H1 receptor antagonist with IC50 of 3 nM. Clemastine Fumarate chemical structure
  9. BCC1486 Clemizole hydrochloride Clemizole hydrochloride is an H1 histamine receptor antagonist, is found to substantially inhibit HCV replication. The IC50 of Clemizole for RNA binding by NS4B is 24±1 nM, whereas its EC50 for viral replication is 8 µM. Clemizole hydrochloride chemical structure
  10. BCC4540 Desloratadine Desloratadine(Sch34117) is a potent antagonist for human histamine H1 receptor used to treat allergies. Desloratadine chemical structure
  11. BCC7061 (S)-(+)-Dimethindene maleate 136152-65-3 (S)-(+)-Dimethindene maleate chemical structure

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