Stress and Anxiety Research

Stress is a valuable evolutionary-conserved physiological response to threatening or adverse environments. Chronic stress is a pathological state that is caused by prolonged upregulation of the normal acute stress response. Anxiety disorders, such as phobias and post-traumatic stress disorder, are due to fear conditioning to a neutral stimulus and involve many of the same brain regions as stress.

Stress and Anxiety Research Products Targets

Products for Stress and Anxiety Research - Page 17

Cat.No. Product Name Information/Activity
BCC6919 PD 168077 maleate PD-168077 maleate is a selective dopamine D4 receptor agonist, with a Ki of 9 nM.
BCC7330 Ro 10-5824 dihydrochloride Ro 10-5824 dihydrochloride is a selective dopamine D4 receptor partial agonist, with Ki of 5.2 nM.
BCC2054 WAY-100635 maleate salt WAY-100635 maleate salt is a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC50 value of 0.91 nM and Ki value of 0.39 nM. WAY-100635 maleate salt has pIC50 values for 5-HT1A and α1-adrenergic receptors of 8.9 and 6.6, respectively. WAY-100635 maleate salt is also a potent dopamine D4 receptor agonist.
BCC7440 Fananserin Fananserin (RP 62203) is an orally bioavailable, potent and selective 5-hydroxytryptamine2 (5-HT2) receptor antagonist, with a Ki of 0.37 nM for the rat 5-HT2A receptor. Fananserin also is a selective dopamine D4 receptor antagonist, with a Ki of 2.93 nM for the human dopamine D4 receptor.
BCC5696 L-741,742 hydrochloride 874882-93-6
BCC5695 L-745,870 trihydrochloride 866021-03-6
BCC7702 PD 168568 dihydrochloride 210688-56-5
BCC7467 PNU 96415E 170856-41-4
BCC7879 Sonepiprazole 170858-33-0
BCC7636 NGD 94-1 178928-68-2