Neurotransmission

Neurotransmission, or synaptic transmission, involves the passage of signals by electrical or chemical means from one neuron to another. It allows communication between nerve cells for the propagation of electrical impulses to and from the central nervous system leading to the co-ordination of secretion, muscle contraction and organ function.

Neurotransmission Products Targets

Products for Neurotransmission - Page 63

Cat.No. Product Name Information/Activity
BCC6609 L-CCG-l 117857-93-9
BCC5691 DCG IV DCG-IV is a potent agonist of group II mGluRs with EC50s of 0.35 and 0.09 μM for mGlu2R and mGlu3R, reapectively. DCG-IV is also a competitive antagonist at group I (IC50: mGlu1/5R=389/630 μM) and III receptors (IC50: mGlu4/6/7/8R= 22.5/39.6/40.1/32 μM). DCG-IV has anticonvulsive and neuroprotective effects.
BCC7614 LY 354740 Eglumegad (LY354740) is a highly potent and selective group II (mGlu2/3) receptor agonist with IC50s of 5 and 24 nM on transfected human mGlu2 and mGlu3 receptors, respectively.
BCC7368 LY 379268 Highly selective group II mGlu agonist
BCC7623 (±)-LY 395756 852679-66-4
BCC6758 MAP4 157381-42-5
BCC6925 (RS)-APICA 170847-18-4
BCC6871 EGLU EGLU ((2S)-α-Ethylglutamic acid; (2S)-α-EGLU) is a potent and competitive mGluR-2 receptor antagonist. EGLU interacts with (lS,3S)-ACPD-sensitive site with a Kd value of 66 μM. EGLU is an antidepressant agent.
BCC1724 LY341495 LY341495 is a metabotropic glutamate receptor (mGluR) antagonist with IC50s of 2.9 nM, 10 nM, 170 nM for mGluR-2, mGluR-3, mGluR-8, respectively.
BCC6819 MSPG 169209-64-7