Neurotransmission
Neurotransmission, or synaptic transmission, involves the passage of signals by electrical or chemical means from one neuron to another. It allows communication between nerve cells for the propagation of electrical impulses to and from the central nervous system leading to the co-ordination of secretion, muscle contraction and organ function.
Neurotransmission Products Targets
- GABAB Receptor (28)
- Others (20)
- Nucleoside Transporter (5)
- Glycine Transporter (6)
- GABA (10)
- Cannabinoid Transporter (10)
- Acetylcholine Transporter (1)
- D4 Receptor (12)
- 5-HT7 Receptor (11)
- 5-HT6 Receptor (14)
- 5-ht5 Receptor (2)
- 5-HT4 Receptor (17)
- NOP Receptor (21)
- Mu-Opioid Receptors (15)
- Kappa Opioid Receptors (14)
- Glutamate (Metabotropic) Group III Receptor (26)
- Glutamate (Metabotropic) Group II Receptor (33)
- Glutamate (Metabotropic) Group I Receptor (54)
- AMPA Receptor (45)
- GABAA-ρ Receptor (8)
- GABAA Receptor (66)
- GPR55 (8)
- CB2 Receptor (6)
- CB1 Receptor (17)
- Nicotinic (α7) Receptor (25)
- Nicotinic (α4β2) Receptor (14)
- Purinergic (P2Y) Receptors (31)
- Purinergic (P2X) Receptors (32)
- Glycine Receptors (6)
- D3 Receptor (12)
- Vesicular Monoamine Transporter (4)
- NMDA Receptor (87)
- Kainate Receptor (22)
- D2 Receptor (14)
- D1 and D5 Receptor (16)
- Glutamate Transporter (18)
- Dopamine Transporter (20)
- Histamine H4 Receptor (12)
- Histamine H3 Receptor (22)
- Histamine H2 Receptor (10)
- Histamine H1 Receptor (17)
- Adrenergic Transporter (23)
- 5-HT Transporter (30)
- NO donors and precursors (9)
- nNOS (5)
- iNOS (11)
- eNOS (1)
- M5 Receptor (2)
- M4 Receptor (3)
- M3 Receptor (4)
- M2 Receptor (5)
- M1 Receptor (8)
- Delta opioid receptor (16)
- Adrenergic α2 Receptor (33)
- Adrenergic α1 Receptor (22)
- Adrenergic β3 Receptor (12)
- Adrenergic β2 Receptor (6)
- Adrenergic β1 Receptor (7)
Products for Neurotransmission - Page 44
- Cat.No. Product Name Information/Activity
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BCC6378
Talampanel(LY300164)
Talampanel is a potent and selective AMPA-receptor antagonist, is a potential new antiepileptic drug (AED).
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BCC7171
UBP 282
544697-47-4
-
BCC7455
YM 90K hydrochloride
154164-30-4
-
BCC7339
ZK 200775
Fanapanel (ZK200775) is a highly selective AMPA/kainate antagonist with little activity against NMDA; have Ki values of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively.
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BCC6151
CMPDA
CMPDA is a positive allosteric modulator of AMPA receptors with EC50s of 45.4 ± 4.2 nM/63.4 ± 5.6 nM for GluA2i/GluA2o receptor.
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BCC7532
CX 546
CX546 is a selective positive AMPAR modulator; the prototypical ampakine agent.
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BCC6759
Cyclothiazide
2259-96-3
-
BCC5951
PEPA
PEPA is an allosteric modulator of AMPA receptors; binds to the GluA2o and GluA3o LBDs and can be utilized as an indicator of AMPA receptor heterogeneity.
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BCC6322
PF 4778574
PF-4778574 is a positive allosteric modulation of AMPA receptor with EC50 of 45 to 919 nM in differenct cells.
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BCC6081
S 18986
S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors. S 18986 shows cognitive enhancing properties in rodents. S 18986 activates the release of noradrenaline and acetylcholine in rat hippocampus and enhances rat memory in object-recognition tests.
