Stem Cell Differentiation
Stem cell differentiation involves the changing of a cell to a more specialized cell type, involving a switch from proliferation to specialization. This involves a succession of alterations in cell morphometry, membrane potential, metabolic activity and signal responsiveness.
Products for Stem Cell Differentiation - Page 5
- Cat.No. Product Name Information/Activity
-
BCC6390
SAG
SAG is a potent Smo receptor agonist which activates the Hedgehog signaling pathway with a Kd of 59 nM.
-
BCC3658
SB 431542
SB-431542 is a potent and selective inhibitor of ALK5/TGF-β type I Receptor with an IC50 value of 94 nM.
-
BCC6334
Shz 1
326886-05-9
-
BCC4720
Sodium butyrate
Sodium Butyrate (Butanoic acid sodium salt) is a histone deacetylase (HDAC) inhibitor, with anti-tumor effects in several cancers.
-
BCC2474
SP 600125
JNK inhibitor; prevents BMP9-induced osteogenic differentiation of MSCs,SP600125 is a broad-spectrum JNK inhibitor for JNK1, JNK2 and JNK3 with IC50 of 40 nM, 40 nM and 90 nM in cell-free assays, respectively; 10-fold greater selectivity against MKK4, 25-fold greater selectivity against MKK3, MKK6, PKB, and PKCα, and 100-fold selectivity against ERK2, p38, Chk1, EGFR etc.
-
BCC7768
Stauprimide
Stauprimide is a staurosporine analog that promotes embryonic stem cell (ESC) differentiation. Stauprimide is a non-broad spectrum inhibitor that binds to the MYC transcription factor NME2 and blocks its nuclear localization in ESCs, which results in down-regulation of MYC transcription.
-
BCC7938
STF 31
STF-31 is an inhibitor of glucose transporter 1 (GLUT1, IC50 = 1 μM).
-
BCC7973
Strontium chloride
10476-85-4
-
BCC1970
SU 5402
SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGFRβ, respectively.
-
BCC7798
TCS 2210
1201916-31-5
