Neural Development

Neural development describes the growth and development of the nervous system starting from embryogenesis and continuing throughout life.

Neural Development Products Targets

Cat.No. Product Name Information/Activity
BCC5401 iCRT 14 iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT), with IC50 of 40.3 nM against Wnt responsive STF16 luciferase.
BCC7823 exo-IWR 1 1127442-87-8
BCC6251 JW 67 442644-28-2
BCC7704 PNU 74654 PNU-74654 is an inhibitor of Wnt/β-catenin pathway with an IC50 of 129.8 μM in NCI-H295 cell.
BCC3968 TAK-715 TAK-715 is a p38 MAPK inhibitor for p38α with IC50 of 7.1 nM, 28-fold more selective for p38α over p38β, no inhibition to p38γ/δ, JNK1, ERK1, IKKβ, MEKK1 or TAK1.
BCC1508 D4476 D4476 is a potent, selective and cell-permeable inhibitor of casein kinase 1(CK1) with an IC50 value of 0.3 μM in vitro.
BCC7726 (R)-DRF053 dihydrochloride Dual cdk1/cdk5 inhibitor. Also inhibits CK1
BCC4246 LH846 LH846 is a selective inhibitor of CKIδ, with an IC50 of 290 nM, and less potently inhibits CKIα and CKIε, with IC50s of 2.5 μM and 1.3 μM, respectively.
BCC7904 PF 4800567 hydrochloride 1391052-28-0
BCC1856 PF-670462 PF-670462 is a potent and selective inhibitor of casein kinase (CK1ε and CK1δ), with IC50s of 7.7 nM and 14 nM, respectively.