Voltage-gated Potassium (KV) Channel
Voltage-gated potassium channels (KV) belong to the 6-TM family of potassium channel that also comprises the Ca2+-activated Slo (actually 7-TM) and the Ca2+-activated SK subfamilies. The α -subunits contain a single pore-forming region and combine to form tetramers.
Products for Voltage-gated Potassium (KV) Channel - Page 4
- Cat.No. Product Name Information/Activity
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BCC7927
Psora 4
Potent K<sub>V</sub>1.3 channel blocker
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BCC6044
RuBi-4AP
851956-02-0
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BCC5990
ShK-Dap22
220384-25-8
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BCC3866
Terfenadine
Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9.
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BCC7554
Tetraethylammonium chloride
Non-selective K<sup>+</sup> channel blocker
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BCC7784
UK 78282 hydrochloride
136647-02-4
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BCC7232
XE 991 dihydrochloride
XE 991 dihydrochloride, a Kv7 (KCNQ) channels blocker, potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current with IC50s of 0.75 µM, 0.71 µM, 0.6 μM, and 0.98 µM, respectively.
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BCC4907
Fluticasone propionate
Fluticasone propionate is a high affinity, selective GR (glucocorticoid receptor) agonist which is derived from fluticasone used to treat asthma and allergic rhinitis.
