Immunology Research

Immunology is a branch of science that studies all aspects of the immune system, ranging from normal physiological functioning through to malfunctions which can lead to immunological diseases. Disorders that result from aberrant activation of the immune system are termed autoimmune diseases.

Immunology Research Products Areas

Products for Immunology Research - Page 39

Cat.No. Product Name Information/Activity
BCC4308 A 419259 trihydrochloride A 419259 trihydrochloride is a Src family kinases inhibitor with IC50s of 9 nM, 3 nM and 3 nM for Src, Lck and Lyn, respectively.
BCC1167 Bosutinib (SKI-606) Bosutinib is a dual Src/Abl inhibitor with IC50s of 1.2 nM and 1 nM, respectively.
BCN5539 Damnacanthal Damnacanthal is an anthraquinone isolated from the root of Morinda citrifolia. Damnacanthal is a highly potent, selective inhibitor of p56lck tyrosine kinase activity. Natural Damnacanthal inhibits p56 lck autophosphorylation and phosphorylation of exogenous substrates with IC50s of 46 nM and 220 nM, respectively. Damnacanthal is a potent inducer of apoptosis with anticancer activity. Damnacanthal also has antinociceptive, anti-inflammatory effects in mice and anti-fungal activity against Candida albicans.
BCC7132 Herbimycin A Antiangiogenic. Inhibits Src family kinases and Hsp90
BCC6253 KB SRC 4 KB SRC 4 is a potent, and highly selective c-Src inhibitor, with a Ki of 44 nM and a Kd of 86 nM, and shows no inhibition on c-Abl up to 125 μM; KB SRC 4 has antitumor activity.
BCN1808 Lavendustin A Lavendustin A (RG-14355), isolated from Streptomyces Griseolavendus, is a potent, specific and ATP-competitive inhibitor of tyrosine kinase, with an IC50 of 11 ng/mL for EGFR-associated tyrosine kinase. It suppresses VEGF-induced angiogenesis and blocks the induction of LTPGABA-A.
BCC3893 1-Naphthyl PP1 1-Naphthyl PP1(1-NA-PP 1) is a selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl (IC50 values are 1.0, 0.6, 0.6, 18 and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II respectively).
BCC3894 PD 180970 p210<sup>Bcr/Abl</sup> kinase inhibitor; also inhibits c-Src and KIT
BCC3630 PP 1 PP1 is a potent, and Src family-selective tyrosine kinase inhibitor with IC50 of 5 and 6 nM for Lck and Fyn, respectively.
BCC3631 PP 2 (AG 1879) PP2 is a reversible and ATP-competitive Src family kinases inhibitor with IC50s of 4 and 5 nM for Lck and Fyn, respectively.