Other Nuclear Receptors

Cat.No. Product Name Information/Activity

BCC7929 DLPC Selective liver receptor homolog-1 (LRH-1) agonist DLPC chemical structure

BCC1957 Sobetirome Sobetirome is a thyroid hormone receptor β (TRβ)-specific agonist which bind selectively to TRβ-1 with an EC50 of 0.16 μM. Sobetirome chemical structure

BCC6026 SID 7969543 868224-64-0 SID 7969543 chemical structure

BCN3793 Guggulsterone Z Guggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii. Guggulsterone inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products (IAP1, xIAP, Bfl-1/A1, Bcl-2, cFLIP and survivin), modulation of cell cycle proteins (cyclin D1 and c-Myc), activation of caspases and JNK, inhibition of Akt. Guggulsterone, a farnesoid X receptor (FXR) antagonist, decreases CDCA-induced FXR activation with IC50s of 17 and 15 μM for Z- and E-Guggulsterone, respectively. Guggulsterone Z chemical structure

BCC7712 Z-Guggulsterone Z-guggulsterone, a constituent of Indian Ayurvedic medicinal plant Commiphora mukul, inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis. Z-Guggulsterone chemical structure

BCN1419 3,3'',5-Triiodo-L-thyronine Sodium Salt Liothyronine sodium is an active form of thyroid hormone, which binds to β1 thyroid hormone receptor (TRβ1), and activates its activity.

3,3'',5-Triiodo-L-thyronine Sodium Salt chemical structure

Products for Other Nuclear Receptors