NPY Receptor
Neuropeptide Y (NPY) receptors are a family of Gi/o-protein-coupled receptors that are currently divided into four subtypes: Y1, Y2, Y4 and Y5. NPY receptors mediate a diverse range of biological actions including stimulation of food intake and modulation of circadian rhythm.
Products for NPY Receptor - Page 2
- Cat.No. Product Name Information/Activity
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BCC5882
BVD 10
Highly selective NPY Y<sub>1</sub> receptor antagonist; devoid of Y<sub>4</sub> agonist activity
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BCC7283
CGP 71683 hydrochloride
CGP71683 hydrochloride is a competitive neuropeptide Y5 receptor antagonist with a Ki of 1.3 nM, and shows no obvious activity at Y1 receptor (Ki, >4000 nM) and Y2 receptor (Ki, 200 nM) in cell membranes.
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BCC6238
CYM 9484
CYM 9484 is a selective and highly potent neuropeptide Y (NPY) Y2 receptor antagonist with an IC50 value of 19 nM.
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BCC6100
JNJ 5207787
JNJ-5207787 is a nonpeptidic, selective and penetrate the blood-brain barrier neuropeptide Y Y2 receptor (Y2) antagonist. JNJ-5207787 inhibits the binding of peptide YY (PYY) with pIC50s of 7.0 and 7.1 for human Y2 receptor and rat Y2 receptor, respectively. JNJ-5207787 is >100-fold selective versus human Y1, Y4, and Y5 receptors.
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BCC7041
L-152,804
L 152804 is an orally active and selective neuropeptide Y Y5 receptor (NPY5-R) antagonist, with a Ki of 26 nM for hY5. L 152804 causes weight loss in diet-induced obese mice by modulating food intake and energy expenditure.
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BCC7708
LU AA33810
304008-29-5
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BCC7747
NPY 5RA972
439861-56-0
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BCC7270
NTNCB hydrochloride
191931-56-3
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BCC7284
PD 160170
181468-88-2
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BCC7687
S 25585
263849-50-9
