Motilin Receptor
The motilin receptor is a Gq/11-protein-coupled receptor that mediates progastrokinetic effects. It is found at its highest concentrations in the nerves of the antral wall of the stomach and is also found at significant levels throughout the smooth muscle of the upper GI tract.
Products for Motilin Receptor
- Cat.No. Product Name Information/Activity
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BCC5894
Motilin (human, porcine)
Motilin (26-47), human, porcine is an endogenous motilin receptor ligand with Ki and EC50 of 2.3 nM and 0.3 nM in a Chinese hamster ovary cell line.
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BCC6359
ANQ 11125
Selective motilin receptor antagonist
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BCC7983
MA 2029
MA-2029 is a selective, orally active, and competitive motilin receptor antagonist (IC50=4.9 nM). MA-2029 is selective for the motilin receptor over various other receptors and ion channels. MA-2029 may be useful for gastrointestinal disorders associated with disturbed gastrointestinal motility.
