Melanocortin (MC) Receptor
Melanocortin receptors are activated by members of the melanocortin family: α -, β - and γ -melanocyte stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH). The melanocortins are involved in a range of physiological functions, including pigmentation and inflammation.
Products for Melanocortin (MC) Receptor
- Cat.No. Product Name Information/Activity
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BCC6028
ACTH (1-39)
Adrenocorticotropic Hormone (ACTH) (1-39), human is a melanocortin receptor agonist.
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BCC7850
BMS 470539 dihydrochloride
Potent, selective MC<sub>1</sub> receptor agonist
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BCC7414
Melanotan II
Melanotan (MT)-II, a synthetic melanocortin receptor agonist, is an injectable peptide hormone used to promote tanning.
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BCC6021
γ1-MSH
72629-65-3
-
BCC7902
[D-Trp8]-γ-MSH
321351-81-9
-
BCC7420
α-MSH
α-Melanocyte-Stimulating Hormone (MSH), amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase.
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BCC5963
[Nle4,D-Phe7]-α-MSH
Melanotan I is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH), for gaining a tan.
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BCC6363
PG 931
667430-81-1
-
BCC7539
THIQ
THIQ is the first selective agonist of the melanocortin-4 receptor (MC4R), with high affinity and potency for hMC4R (IC50=1.2 nM, EC50=2.1 nM) and rMC4R (IC50=0.6 nM, EC50=2.9 nM). THIQ maintains low potency at MC1R, MC3R and MC5R. THIQ plays a role in eliciting erectile activity in rodents. THIQ acts as a pharmacoperone of the MC4R rescuing the cell surface expression and signaling of some intracellularly retained MC4R mutants.
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BCC5819
HS 014
207678-81-7


