Melanocortin (MC) Receptor

Melanocortin receptors are activated by members of the melanocortin family: α -, β - and γ -melanocyte stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH). The melanocortins are involved in a range of physiological functions, including pigmentation and inflammation.

Products for Melanocortin (MC) Receptor

  1. Cat.No. Product Name Information/Activity
  2. BCC6028 ACTH (1-39) Adrenocorticotropic Hormone (ACTH) (1-39), human is a melanocortin receptor agonist. ACTH (1-39) chemical structure
  3. BCC7850 BMS 470539 dihydrochloride Potent, selective MC<sub>1</sub> receptor agonist BMS 470539 dihydrochloride chemical structure
  4. BCC7414 Melanotan II Melanotan (MT)-II, a synthetic melanocortin receptor agonist, is an injectable peptide hormone used to promote tanning. Melanotan II chemical structure
  5. BCC6021 γ1-MSH 72629-65-3 γ1-MSH chemical structure
  6. BCC7902 [D-Trp8]-γ-MSH 321351-81-9 [D-Trp8]-γ-MSH chemical structure
  7. BCC7420 α-MSH α-Melanocyte-Stimulating Hormone (MSH), amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase. α-MSH chemical structure
  8. BCC5963 [Nle4,D-Phe7]-α-MSH Melanotan I is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH), for gaining a tan. [Nle4,D-Phe7]-α-MSH chemical structure
  9. BCC6363 PG 931 667430-81-1 PG 931 chemical structure
  10. BCC7539 THIQ THIQ is the first selective agonist of the melanocortin-4 receptor (MC4R), with high affinity and potency for hMC4R (IC50=1.2 nM, EC50=2.1 nM) and rMC4R (IC50=0.6 nM, EC50=2.9 nM). THIQ maintains low potency at MC1R, MC3R and MC5R. THIQ plays a role in eliciting erectile activity in rodents. THIQ acts as a pharmacoperone of the MC4R rescuing the cell surface expression and signaling of some intracellularly retained MC4R mutants. THIQ chemical structure
  11. BCC5819 HS 014 207678-81-7 HS 014 chemical structure

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