ETB Receptor

The endothelinB receptor (ETB receptor) is a member of the endothelin receptor group of G-protein-coupled receptors that also includes ETA. They are located primarily in vascular endothelial cells where they play a role in vasoconstriction, vasodilation and cell proliferation.

Products for ETB Receptor

Cat.No. Product Name Information/Activity
BCC5728 BQ-3020 Selective ET<sub>B</sub> agonist
BCC5731 [Ala1,3,11,15]-Endothelin 121204-87-3
BCC5721 Sarafotoxin S6c 121695-87-2
BCC5151 BQ-788 sodium salt BQ-788 (sodium salt) is a potent and selective ETB receptor antagonist, inhibiting ET-1 binding to ETB receptors with an IC50 of 1.2 nM in human Girrardi heart cells.
BCC7192 IRL-2500 IRL 2500 is a potent Endothelin receptor antagonist. IRL 2500 shows IC50 values of 1.3 and 94 nM for ETB and ETA receptors, respectively. IRL 2500 inhibits ETB receptor-mediated blood pressure increase and renal vascular resistance in rats in vivo.
BCC5730 IRL-1038 144602-02-8