PPARγ
Peroxisome proliferator-activated receptor gamma (PPARγ ) is a member of the nuclear receptor family of ligand-activated transcription factors that heterodimerize with the retinoic X receptor (RXR) to regulate gene expression.
Products for PPARγ - Page 2
- Cat.No. Product Name Information/Activity
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BCC1573
FH535
FH535 is an inhibitor of Wnt/β-catenin and PPAR, with anti-tumor activities.
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BCC2260
GW9662
GW9662 is a potent and selective PPARγ antagonist with an IC50 of 3.3 nM, showing 10 and 1000-fold selectivity over PPARα and PPARδ, respectively.
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BCC7243
SR 202
Mifobate (SR-202) is a potent and specific PPARγ antagonist. Mifobate (SR-202) selectively inhibits Thiazolidinedione (TZD)-induced PPARγ transcriptional activity (IC50=140 μM). Mifobate (SR-202) does not affect basal or ligand-stimulated transcriptional activity of PPARα, PPARβ, or the farnesoid X receptor (FXR). Mifobate (SR-202) shows antiobesity and antidiabetic effects.
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BCC2261
T0070907
T0070907 is a potent PPARγ antagonist with a Ki of 1 nM.
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BCN5499
Genistein
Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis.
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BCC6166
SR 1664
1338259-05-4
