Toddanone

CAS# 77636-08-9

Toddanone

Catalog No. BCN3430----Order now to get a substantial discount!

Product Name & Size Price Stock
Toddanone:5mg Please Inquire In Stock
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Chemical structure

Toddanone

3D structure

Chemical Properties of Toddanone

Cas No. 77636-08-9 SDF Download SDF
PubChem ID 102004726 Appearance Cryst.
Formula C16H18O5 M.Wt 290.3
Type of Compound Coumarins Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 6-[(2S)-2-hydroxy-3-methylbut-3-enyl]-5,7-dimethoxychromen-2-one
SMILES CC(=C)C(CC1=C(C=C2C(=C1OC)C=CC(=O)O2)OC)O
Standard InChIKey RUCHZOCSENTTRO-LBPRGKRZSA-N
Standard InChI InChI=1S/C16H18O5/c1-9(2)12(17)7-11-13(19-3)8-14-10(16(11)20-4)5-6-15(18)21-14/h5-6,8,12,17H,1,7H2,2-4H3/t12-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Toddanone

The roots of Toddalia asiatica

Biological Activity of Toddanone

DescriptionStandard reference
In vitro

Spasmolytic activity of Toddalia asiatica Var. floribunda.[Pubmed: 12164278]

Phytother Res. 2002 May;16(3):281-2.


METHODS AND RESULTS:
The spasmolytic activity of the aerial parts of Toddalia asiatica var. floribunda (family Rutaceae) was evaluated. The ethanol extract exhibited significant spasmolytic activity and was then partitioned into five fractions. The activity was found to be concentrated only in the hexane and chloroform fractions.
CONCLUSIONS:
This activity was shown not to be due to the coumarins, toddalolactone and Toddanone, as was previously thought.

Antifeedant activity of twenty six plant extracts and pure compounds from the root bark of Toddalia asiatica (L) (Rutaceae) against the anomalous emperor moth Nudaurelia belina (Saturnidae)[Reference: WebLink]

Huria Journal of the Open University of Tanzania, 2012 , 12 (1).

The antifeedant activity of petroleum ether (PE) (40-60%) extract of the root bark of T. asiatica and twenty five other plant extracts was investigated against the anomalous emperor moth N. belina.
METHODS AND RESULTS:
The petroleum ether extract of stem bark of Albizia anthelmintica, leaves of Cassia occidentalis, Balanites aegyptica, seeds of Cucumis sativaus, root bark of T. asiatica, root bark of Celtis durandii, B. aegyptica and whole plant of Cisus quadrangularis were found to be active against N. belina at a concentration of 1% w/v in a modified leaf disc method. Also, methanol extracts of the root bark of A. muricata and Eucalyptus spp were found to be active against N. belina at a concentration of 1% w/v.
CONCLUSIONS:
Three cumarius; dihydrotoddanol, toddanol and toddalactone and the alkaloid dihydrochelerynthrine isolated from the PE extract of the root bark of T. asiatica exhibited antifeedant activity at as low as 0.05% w/v. Toddaculine and Toddanone which were also isolated from the P.E. extract had no activity at 0.05% w/v.

Toddanone Dilution Calculator

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Toddanone Molarity Calculator

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Preparing Stock Solutions of Toddanone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.4447 mL 17.2236 mL 34.4471 mL 68.8942 mL 86.1178 mL
5 mM 0.6889 mL 3.4447 mL 6.8894 mL 13.7788 mL 17.2236 mL
10 mM 0.3445 mL 1.7224 mL 3.4447 mL 6.8894 mL 8.6118 mL
50 mM 0.0689 mL 0.3445 mL 0.6889 mL 1.3779 mL 1.7224 mL
100 mM 0.0344 mL 0.1722 mL 0.3445 mL 0.6889 mL 0.8612 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Toddanone

Spasmolytic activity of Toddalia asiatica Var. floribunda.[Pubmed:12164278]

Phytother Res. 2002 May;16(3):281-2.

The spasmolytic activity of the aerial parts of Toddalia asiatica var. floribunda (family Rutaceae) was evaluated. The ethanol extract exhibited significant spasmolytic activity and was then partitioned into five fractions. The activity was found to be concentrated only in the hexane and chloroform fractions. This activity was shown not to be due to the coumarins, toddalolactone and Toddanone, as was previously thought.

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