Stilbostemin BCAS# 162411-67-8 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 162411-67-8 | SDF | Download SDF |
| PubChem ID | 10376477 | Appearance | Powder |
| Formula | C15H16O2 | M.Wt | 228.29 |
| Type of Compound | Phenols | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 2-methyl-5-(2-phenylethyl)benzene-1,3-diol | ||
| SMILES | CC1=C(C=C(C=C1O)CCC2=CC=CC=C2)O | ||
| Standard InChIKey | ZGLHZPWZOCCDAY-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C15H16O2/c1-11-14(16)9-13(10-15(11)17)8-7-12-5-3-2-4-6-12/h2-6,9-10,16-17H,7-8H2,1H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Stilbostemin A, stilbostemin B , stilbostemin D , stilbostemin F , and stilbostemin G show structure-dependent inhibition of leukotriene biosynthesis with IC(50) values ranging from 3.7 to >50 microM. |
Stilbostemin B Dilution Calculator
Stilbostemin B Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.3804 mL | 21.902 mL | 43.8039 mL | 87.6079 mL | 109.5098 mL |
| 5 mM | 0.8761 mL | 4.3804 mL | 8.7608 mL | 17.5216 mL | 21.902 mL |
| 10 mM | 0.438 mL | 2.1902 mL | 4.3804 mL | 8.7608 mL | 10.951 mL |
| 50 mM | 0.0876 mL | 0.438 mL | 0.8761 mL | 1.7522 mL | 2.1902 mL |
| 100 mM | 0.0438 mL | 0.219 mL | 0.438 mL | 0.8761 mL | 1.0951 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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[Chemical constituents from Glechoma longituba].[Pubmed:25204149]
Zhongguo Zhong Yao Za Zhi. 2014 Feb;39(4):695-8.
Fourteen compounds were obtained from Glechoma longituba by the chromatographic methods of silica gel, ODS, Sephadex LH-20 and preparative of HPLC. According to physicochemical properties and spectral data, these compounds were identified as Stilbostemin B (1), trilepisiumic acid (2), 3, 4-dihydroxyphenyl ethanol ketone (3), bergeninmonohydrate (4), oresbiusin A (5), norbergenin (6), stilbostemin D (7), ehretioside B (8), ethyl ferulate (9), E-p-hydroxy-cinnamic acid (10), methyl gallate (11), protocatechuic acid (12), 4'-Hydroxyacetophenone (13), and E-3-2,4-dihydroxyphenyl-2-acrylic acid (14). Among them, compounds 1-10, 13 and 14 were isolated from this plant for the first time.
Neuroprotective bibenzyl glycosides of Stemona tuberosa roots.[Pubmed:16643052]
J Nat Prod. 2006 Apr;69(4):679-81.
Three new bibenzyl glycosides characterized as Stilbostemin B 3'-beta-D-glucopyranoside (1), stilbostemin H 3'-beta-D-glucopyranoside (2), and stilbostemin I 2"-beta-D-glucopyranoside (3) were isolated from the roots of Stemona tuberosa. All three bibenzyl glycosides significantly protected human neuroblastoma SH-SY5Y cells from 6-hydroxydopamine-induced neurotoxicity.
Inhibition of leukotriene biosynthesis by stilbenoids from Stemona species.[Pubmed:15679323]
J Nat Prod. 2005 Jan;68(1):83-5.
Fifteen stilbenoids and two alkaloids from Stemona collinsae, S. tuberosa, and S. peirrei were tested alongside the commercially available stilbenoids resveratrol and pinosylvin for inhibition of leukotriene formation in an ex vivo test system based on activated human neutrophilic granulocytes. The stilbenoids resveratrol (1), pinosylvin (2), dihydropinosylvin (3), stilbostemin A (4), Stilbostemin B (5), stilbostemin D (6), stilbostemin F (7), stilbostemin G (8), stemofuran B (9), stemofuran C (10), stemofuran D (11), stemofuran G (12), stemofuran J (13), stemanthrene A (14), stemanthrene B (15), stemanthrene C (16), and stemanthrene D (17) showed structure-dependent activities with IC(50) values ranging from 3.7 to >50 microM. The alkaloids tuberostemonine (18) and neotuberostemonine (19) were inactive at a concentration of 50 microM.
