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Rhein-8-glucoside calcium salt

CAS# 113443-70-2

Rhein-8-glucoside calcium salt

Catalog No. BCN6349----Order now to get a substantial discount!

Product Name & Size Price Stock
Rhein-8-glucoside calcium salt:5mg $94.00 In Stock
Rhein-8-glucoside calcium salt:10mg Please Inquire Instock
Rhein-8-glucoside calcium salt:20mg Please Inquire Instock
Rhein-8-glucoside calcium salt:50mg Please Inquire Instock

Quality Control of Rhein-8-glucoside calcium salt

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Chemical structure

Rhein-8-glucoside calcium salt

3D structure

Chemical Properties of Rhein-8-glucoside calcium salt

Cas No. 113443-70-2 SDF Download SDF
PubChem ID 54676854 Appearance Yellow powder
Formula C21H16CaO11 M.Wt 484.43
Type of Compound Anthraquinones Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name calcium;3-carboxy-9,10-dioxo-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]anthracene-1,8-diolate
SMILES C1=CC(=C2C(=C1C3C(C(C(C(O3)CO)O)O)O)C(=O)C4=CC(=CC(=C4C2=O)[O-])C(=O)O)[O-].[Ca+2]
Standard InChIKey XXVBCAMVOFYHJP-WJGQHNSASA-L
Standard InChI InChI=1S/C21H18O11.Ca/c22-5-11-16(26)18(28)19(29)20(32-11)7-1-2-9(23)14-13(7)15(25)8-3-6(21(30)31)4-10(24)12(8)17(14)27;/h1-4,11,16,18-20,22-24,26,28-29H,5H2,(H,30,31);/q;+2/p-2/t11-,16-,18+,19-,20+;/m1./s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Rhein-8-glucoside calcium salt

The roots of Rheum palmatum L.

Biological Activity of Rhein-8-glucoside calcium salt

DescriptionRhein-8-O-beta-D-glucopyranoside(Rhein-8-glucoside calcium salt) shows moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro.
TargetshPTP1B
In vitro

PTP1B inhibitors from Saussrurea lappa.[Pubmed: 16864436 ]

J Asian Nat Prod Res. 2006 Apr-May;8(3):281-6.


METHODS AND RESULTS:
A new lignan glycoside, named 1,5-dihydroxypinoresinol-4'-O-beta-d-glucopyranoside (1), has been isolated from the EtOH extract of the roots of Saussurea lappa, together with twenty known compounds: (+)-1-hydroxypinoresinol-1-O-beta-D-glucopyranoside (2), fraxiresinol-4'-O-beta-D-glucopyranoside (3), (-)-olivil-4''-O-beta-D-glucopyranoside (4), 4-allyl-2,6-dimethoxybenzene-1-O-beta-D-glucopyranoside, syringin, costunolide-15-O-beta-D-glucopyranoside, chlorogenic acid, aloe-emodin-8-O-beta-D-glucopyranoside (5), rhein-8-O-beta-D-glucopyranoside (Rhein-8-glucoside calcium salt),6), chrysophanol (7), emodin, dehydrocostus lactone, costunolide, beta-costic acid, reynosin, arbusculin A, alpha-cyclocostunolide, beta-cyclocostunolide, santamarine and magnolialide.
CONCLUSIONS:
Three anthraquinones (5-7) showed moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro.

Rhein-8-glucoside calcium salt Dilution Calculator

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Rhein-8-glucoside calcium salt Molarity Calculator

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Preparing Stock Solutions of Rhein-8-glucoside calcium salt

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0643 mL 10.3214 mL 20.6428 mL 41.2856 mL 51.607 mL
5 mM 0.4129 mL 2.0643 mL 4.1286 mL 8.2571 mL 10.3214 mL
10 mM 0.2064 mL 1.0321 mL 2.0643 mL 4.1286 mL 5.1607 mL
50 mM 0.0413 mL 0.2064 mL 0.4129 mL 0.8257 mL 1.0321 mL
100 mM 0.0206 mL 0.1032 mL 0.2064 mL 0.4129 mL 0.5161 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Rhein-8-glucoside calcium salt

PTP1B inhibitors from Saussrurea lappa.[Pubmed:16864436]

J Asian Nat Prod Res. 2006 Apr-May;8(3):281-6.

A new lignan glycoside, named 1,5-dihydroxypinoresinol-4'-O-beta-d-glucopyranoside (1), has been isolated from the EtOH extract of the roots of Saussurea lappa, together with twenty known compounds: (+)-1-hydroxypinoresinol-1-O-beta-D-glucopyranoside (2), fraxiresinol-4'-O-beta-D-glucopyranoside (3), (-)-olivil-4''-O-beta-D-glucopyranoside (4), 4-allyl-2,6-dimethoxybenzene-1-O-beta-D-glucopyranoside, syringin, costunolide-15-O-beta-D-glucopyranoside, chlorogenic acid, aloe-emodin-8-O-beta-D-glucopyranoside (5), rhein-8-O-beta-D-glucopyranoside (6), chrysophanol (7), emodin, dehydrocostus lactone, costunolide, beta-costic acid, reynosin, arbusculin A, alpha-cyclocostunolide, beta-cyclocostunolide, santamarine and magnolialide. Three anthraquinones (5-7) showed moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro.

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