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Methylophiopogonone A

CAS# 74805-90-6

Methylophiopogonone A

Catalog No. BCN2841----Order now to get a substantial discount!

Product Name & Size Price Stock
Methylophiopogonone A:10mg $419.00 In stock
Methylophiopogonone A:20mg $712.00 In stock
Methylophiopogonone A:50mg $1676.00 In stock
Methylophiopogonone A:100mg $2933.00 In stock

Quality Control of Methylophiopogonone A

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Chemical structure

Methylophiopogonone A

3D structure

Chemical Properties of Methylophiopogonone A

Cas No. 74805-90-6 SDF Download SDF
PubChem ID 10065830 Appearance Light yellow powder
Formula C19H16O6 M.Wt 340.33
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in DMSO; slightly soluble in water
Chemical Name 3-(1,3-benzodioxol-5-ylmethyl)-5,7-dihydroxy-6,8-dimethylchromen-4-one
SMILES CC1=C(C2=C(C(=C1O)C)OC=C(C2=O)CC3=CC4=C(C=C3)OCO4)O
Standard InChIKey AUTZLTCWRDPAPV-UHFFFAOYSA-N
Standard InChI InChI=1S/C19H16O6/c1-9-16(20)10(2)19-15(17(9)21)18(22)12(7-23-19)5-11-3-4-13-14(6-11)25-8-24-13/h3-4,6-7,20-21H,5,8H2,1-2H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Methylophiopogonone A

The roots of Ophiopogon japonicus

Biological Activity of Methylophiopogonone A

DescriptionMethylophiopogonone A is a natural product from Ophiopogon japonicus.

Protocol of Methylophiopogonone A

Structure Identification
Chemical & pharmaceutical bulletin,1993, 41(2), 391-393.

Comparative Studies on the Constituents of Ophiopogonis Tuber and Its Congeners. VII. Studies on the Homoisoflavonoids of the Subterranean Part of Ophiopogon japonicus KER-GAWLER cv. Nanus. [Reference: WebLink]


METHODS AND RESULTS:
Six known homoisoflavonoidal compounds (1-6) and three new homoisoflavonoidal compounds (7-9) were isolated from the ether-soluble fraction of the subterranean part of Ophiopogon japonicus KER-GAWLER cv. Nanus. Among them, 1,2,3,4,5 and 6 were identified as Methylophiopogonone A (1), ophiopogonone A (2), methylophiopogonanone A (3), ophiopogonanone A (4), JE-III (5) and desmethylisoophiopogonone B (6), respectively.
CONCLUSIONS:
The structures of compounds 7-9 were elucidated as 5,7,2'-trihydroxy-6-methyl-3-(3', 4'-methylenedioxybenzyl)chromone (7), 5,7,2'-trihydroxy-8-methyl-3-(3', 4'-methylenedioxybenzyl)chromone (8), and a racemate of 5-hydroxy-7,8-dimethoxy-6-methyl-3-(3', 4'-dihydroxybenzyl)chroman-4-one (9), respectively.

Methylophiopogonone A Dilution Calculator

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Methylophiopogonone A Molarity Calculator

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Preparing Stock Solutions of Methylophiopogonone A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.9383 mL 14.6916 mL 29.3832 mL 58.7665 mL 73.4581 mL
5 mM 0.5877 mL 2.9383 mL 5.8766 mL 11.7533 mL 14.6916 mL
10 mM 0.2938 mL 1.4692 mL 2.9383 mL 5.8766 mL 7.3458 mL
50 mM 0.0588 mL 0.2938 mL 0.5877 mL 1.1753 mL 1.4692 mL
100 mM 0.0294 mL 0.1469 mL 0.2938 mL 0.5877 mL 0.7346 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Description

Methylophiopogonone A, a homoisoflavonoid isolated from the tuberous roots of Ophiopogon japonicas, shows anti-inflammatory activity.

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