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Isochamaejasmenin B

CAS# 865852-48-8

Isochamaejasmenin B

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Chemical structure

Isochamaejasmenin B

3D structure

Chemical Properties of Isochamaejasmenin B

Cas No. 865852-48-8 SDF Download SDF
PubChem ID 11753405 Appearance Powder
Formula C32H26O10 M.Wt 570.6
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2S,3S)-3-[(2R,3R)-5,7-dihydroxy-2-(4-methoxyphenyl)-4-oxo-2,3-dihydrochromen-3-yl]-5,7-dihydroxy-2-(4-methoxyphenyl)-2,3-dihydrochromen-4-one
SMILES COC1=CC=C(C=C1)C2C(C(=O)C3=C(C=C(C=C3O2)O)O)C4C(OC5=CC(=CC(=C5C4=O)O)O)C6=CC=C(C=C6)OC
Standard InChIKey BTCICADMSGBCKA-WVKQWSHJSA-N
Standard InChI InChI=1S/C32H26O10/c1-39-19-7-3-15(4-8-19)31-27(29(37)25-21(35)11-17(33)13-23(25)41-31)28-30(38)26-22(36)12-18(34)14-24(26)42-32(28)16-5-9-20(40-2)10-6-16/h3-14,27-28,31-36H,1-2H3/t27-,28+,31-,32+
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Isochamaejasmenin B

The roots of Stellera chamaejasme L.

Biological Activity of Isochamaejasmenin B

Description1. Isochamaejasmenin B demonstrates potent antimitotic and antifungal activity with the minimum inhibitory concentration (MIC) value of 6.25 microg/ml.
TargetsAntifection

Isochamaejasmenin B Dilution Calculator

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Preparing Stock Solutions of Isochamaejasmenin B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.7525 mL 8.7627 mL 17.5254 mL 35.0508 mL 43.8135 mL
5 mM 0.3505 mL 1.7525 mL 3.5051 mL 7.0102 mL 8.7627 mL
10 mM 0.1753 mL 0.8763 mL 1.7525 mL 3.5051 mL 4.3814 mL
50 mM 0.0351 mL 0.1753 mL 0.3505 mL 0.701 mL 0.8763 mL
100 mM 0.0175 mL 0.0876 mL 0.1753 mL 0.3505 mL 0.4381 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Isochamaejasmenin B

Antimitotic and antifungal C-3/C-3''-biflavanones from Stellera chamaejasme.[Pubmed:15997133]

Chem Pharm Bull (Tokyo). 2005 Jul;53(7):776-9.

Two new C-3/C-3'' biflavanones, chamaejasmenin D (1) and Isochamaejasmenin B (2), were isolated from the roots of Stellera chamaejasme, together with five known biflavanones, chamaejasmenin A (3), chamaejasmenin B (4), neochamaejasmin A (5), sikokianin A (6), and chamaejasmenin C (7). Their structures were elucidated by spectroscopic methods, including 2D NMR techniques. Among these compounds, 1-3 demonstrated potent antimitotic and antifungal activity with minimum inhibitory concentration (MIC) values of 6.25, 6.25, and 3.12 microg/ml, respectively.

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