Fmoc-Lys(Mtt)-OH

CAS# 167393-62-6

Fmoc-Lys(Mtt)-OH

Catalog No. BCC3523----Order now to get a substantial discount!

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Fmoc-Lys(Mtt)-OH: 5mg $6 In Stock
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Quality Control of Fmoc-Lys(Mtt)-OH

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Chemical structure

Fmoc-Lys(Mtt)-OH

3D structure

Chemical Properties of Fmoc-Lys(Mtt)-OH

Cas No. 167393-62-6 SDF Download SDF
PubChem ID 10963195 Appearance Powder
Formula C41H40N2O4 M.Wt 624.8
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[[(4-methylphenyl)-diphenylmethyl]amino]hexanoic acid
SMILES CC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)NCCCCC(C(=O)O)NC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46
Standard InChIKey YPTNAIDIXCOZAJ-LHEWISCISA-N
Standard InChI InChI=1S/C41H40N2O4/c1-29-23-25-32(26-24-29)41(30-14-4-2-5-15-30,31-16-6-3-7-17-31)42-27-13-12-22-38(39(44)45)43-40(46)47-28-37-35-20-10-8-18-33(35)34-19-9-11-21-36(34)37/h2-11,14-21,23-26,37-38,42H,12-13,22,27-28H2,1H3,(H,43,46)(H,44,45)/t38-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Fmoc-Lys(Mtt)-OH Dilution Calculator

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Fmoc-Lys(Mtt)-OH Molarity Calculator

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Preparing Stock Solutions of Fmoc-Lys(Mtt)-OH

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.6005 mL 8.0026 mL 16.0051 mL 32.0102 mL 40.0128 mL
5 mM 0.3201 mL 1.6005 mL 3.201 mL 6.402 mL 8.0026 mL
10 mM 0.1601 mL 0.8003 mL 1.6005 mL 3.201 mL 4.0013 mL
50 mM 0.032 mL 0.1601 mL 0.3201 mL 0.6402 mL 0.8003 mL
100 mM 0.016 mL 0.08 mL 0.1601 mL 0.3201 mL 0.4001 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Fmoc-Lys(Mtt)-OH

Preparation of the very acid-sensitive Fmoc-Lys(Mtt)-OH. Application in the synthesis of side-chain to side-chain cyclic peptides and oligolysine cores suitable for the solid-phase assembly of MAPs and TASPs.[Pubmed:7591489]

Int J Pept Protein Res. 1995 May;45(5):488-96.

N alpha-9-Fluorenylmethoxycarbonyl-N epsilon-4=methyltrityl-lysine, [Fmoc-Lys(Mtt)-OH], was prepared in two steps from lysine, in 42% overall yield. The N epsilon-Mtt function can be quantitatively removed upon treatment with 1% TFA in dichloromethane or with a 1:2:7 mixture of acetic acid/trifluoroethanol/dichloromethane for 30 min and 1 h at room temperature, respectively. Under these conditions, groups of the tert-butyl type and peptide ester bonds to TFA-labile resins, such as the 2-chlorodiphenylmethyl- and the Wang-resin, remained intact. The utility of the new derivative in peptide synthesis has been exemplified with the synthesis of a cyclic cholecystokinin analog. As an example of further application, five types of lysine cores suitable for the solid-phase synthesis of one, two or three epitopes containing antigenic peptides or template-assembled synthetic proteins have been synthesized on Merrifield, Wang and 2-chlorodiphenylmethyl resin.

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