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Calystegine N1

CAS# 177794-03-5

Calystegine N1

Catalog No. BCN1866----Order now to get a substantial discount!

Product Name & Size Price Stock
Calystegine N1:5mg Please Inquire In Stock
Calystegine N1:10mg Please Inquire In Stock
Calystegine N1:20mg Please Inquire In Stock
Calystegine N1:50mg Please Inquire In Stock

Quality Control of Calystegine N1

Number of papers citing our products

Chemical structure

Calystegine N1

3D structure

Chemical Properties of Calystegine N1

Cas No. 177794-03-5 SDF Download SDF
PubChem ID 10844965 Appearance Powder
Formula C7H14N2O3 M.Wt 174.2
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1R,2S,3R,4R,5S)-5-amino-8-azabicyclo[3.2.1]octane-2,3,4-triol
SMILES C1CC2(C(C(C(C1N2)O)O)O)N
Standard InChIKey KBZOEWOSIUJWIO-UOYQFSTFSA-N
Standard InChI InChI=1S/C7H14N2O3/c8-7-2-1-3(9-7)4(10)5(11)6(7)12/h3-6,9-12H,1-2,8H2/t3-,4+,5-,6+,7+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Calystegine N1

The leaves of Morus alba L.

Biological Activity of Calystegine N1

DescriptionCalystegin N~ is a weaker inhibitor of glycosidases.
In vitro

Calystegin N1, a Novel Nortropane Alkaloid with a Bridgehead Amino Group from Hyoscyamus niger: Structure Determination and Glycosidase Inhibitory Activities.[Reference: WebLink]

ChemInform, 1996, 27(33).


METHODS AND RESULTS:
Seven calystegins were isolated from the whole plant of Hyoscyamus niger. They are calystegins A 3, A 5, A 6, B t , B 2, B 3, and N 1. The structure of new calystegin A 6 was determined as la,2~,7a-trihydroxy-nor-tropane, and another new Calystegine N1 was elucidated to be a trihydroxy-nor-tropane alkaloid with a bridgehead NH 2 group in the place of a bridgehead OH group in calystegin B 2. Very interestingly, on storage for a half year in a refrigerator, approximately 40% of calystegin N I was nonenzymically converted into calystegin B 2.
CONCLUSIONS:
Calystegin N~ was a weaker inhibitor of glycosidases compared to calystegin B 2 but with the same inhibitory spectrum. However, calystegin N~ inhibited porcine kidney trehalase in a noncompetitive manner, whereas calystegin B 2 inhibited this enzyme in a competitive manner.

Calystegine N1 Dilution Calculator

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Calystegine N1 Molarity Calculator

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Preparing Stock Solutions of Calystegine N1

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.7405 mL 28.7026 mL 57.4053 mL 114.8106 mL 143.5132 mL
5 mM 1.1481 mL 5.7405 mL 11.4811 mL 22.9621 mL 28.7026 mL
10 mM 0.5741 mL 2.8703 mL 5.7405 mL 11.4811 mL 14.3513 mL
50 mM 0.1148 mL 0.5741 mL 1.1481 mL 2.2962 mL 2.8703 mL
100 mM 0.0574 mL 0.287 mL 0.5741 mL 1.1481 mL 1.4351 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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