Baccatin VIIICAS# 1623410-10-5 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 1623410-10-5 | SDF | Download SDF |
| PubChem ID | 125181786 | Appearance | Powder |
| Formula | C33H42O13 | M.Wt | 646.68 |
| Type of Compound | Diterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| SMILES | CC1=C2C(C(C3(C(CC4C(C3C(C(C2(C)C)(C(C1OC(=O)C)O)O)OC(=O)C5=CC=CC=C5)(CO4)OC(=O)C)O)C)O)OC(=O)C | ||
| Standard InChIKey | SMMKFLQKTRZJCF-CAEDTEOSSA-N | ||
| Standard InChI | InChI=1S/C33H42O13/c1-15-22-24(44-17(3)35)26(38)31(7)20(37)13-21-32(14-42-21,46-18(4)36)25(31)28(45-29(40)19-11-9-8-10-12-19)33(41,30(22,5)6)27(39)23(15)43-16(2)34/h8-12,20-21,23-28,37-39,41H,13-14H2,1-7H3/t20-,21+,23+,24+,25-,26-,27-,28-,31+,32-,33+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The twigs and leaves of Taxus yunnanensis.
| Description | 1. Baccatin VIII exhibits inhibitory effects on HL-60 and MCF-7, with IC50 values of 3.44 and 9.67 uM, respectively. |
Baccatin VIII Dilution Calculator
Baccatin VIII Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.5464 mL | 7.7318 mL | 15.4636 mL | 30.9272 mL | 38.659 mL |
| 5 mM | 0.3093 mL | 1.5464 mL | 3.0927 mL | 6.1854 mL | 7.7318 mL |
| 10 mM | 0.1546 mL | 0.7732 mL | 1.5464 mL | 3.0927 mL | 3.8659 mL |
| 50 mM | 0.0309 mL | 0.1546 mL | 0.3093 mL | 0.6185 mL | 0.7732 mL |
| 100 mM | 0.0155 mL | 0.0773 mL | 0.1546 mL | 0.3093 mL | 0.3866 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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New Taxane Diterpenoids from Taxus yunnanensis.[Pubmed:24660136]
Nat Prod Bioprospect. 2014 Feb;4(1):47-51.
Three hitherto unknown taxane diterpenoids, namely Baccatin VIII (1), baccatin IX (2), and baccatin X (3), along with 10 known analogues were isolated from an ethanolic extract of the twigs and leaves of Taxus yunnanensis. The new structures were characterized based on extensive spectroscopic analysis. Compounds 1 and 2 were tested for their in vitro cytotoxicity against five human tumor cell lines, and 1 exhibited inhibitory effects on HL-60 and MCF-7, with IC50 values of 3.44 and 9.67 muM, respectively.
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