6-Amino-1-methyl-5-nitrosouracilCAS# 6972-78-7 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 6972-78-7 | SDF | Download SDF |
| PubChem ID | 81448 | Appearance | Powder |
| Formula | C5H6N4O3 | M.Wt | 170 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 6-amino-1-methyl-5-nitrosopyrimidine-2,4-dione | ||
| SMILES | CN1C(=C(C(=O)NC1=O)N=O)N | ||
| Standard InChIKey | AHOWVSJPUQTRNN-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C5H6N4O3/c1-9-3(6)2(8-12)4(10)7-5(9)11/h6H2,1H3,(H,7,10,11) | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
6-Amino-1-methyl-5-nitrosouracil Dilution Calculator
6-Amino-1-methyl-5-nitrosouracil Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 5.8824 mL | 29.4118 mL | 58.8235 mL | 117.6471 mL | 147.0588 mL |
| 5 mM | 1.1765 mL | 5.8824 mL | 11.7647 mL | 23.5294 mL | 29.4118 mL |
| 10 mM | 0.5882 mL | 2.9412 mL | 5.8824 mL | 11.7647 mL | 14.7059 mL |
| 50 mM | 0.1176 mL | 0.5882 mL | 1.1765 mL | 2.3529 mL | 2.9412 mL |
| 100 mM | 0.0588 mL | 0.2941 mL | 0.5882 mL | 1.1765 mL | 1.4706 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Synthesis, characterization and antimicrobial studies on cis-platinum(II) complexes of 5-nitrosouracil derivatives.[Pubmed:19889573]
Spectrochim Acta A Mol Biomol Spectrosc. 2010 Jan;75(1):146-51.
Two complexes were obtained during the reactions of 6-Amino-1-methyl-5-nitrosouracil (AMNU) and 6-methylamino-1-benzyl-5-nitrosouracil (MABNU) with cis-diaquadiamineplatinum(II) nitrate complex, cis-[Pt(NH(3))(2)(H(2)O)(2)](NO(3))(2). The complexes were isolated in good yields as powdery precipitates. They were characterized through their elemental analysis, infrared, UV-vis, and (1)H NMR spectroscopies as well as thermal analyses. The obtained results indicated that, pyrimidine bases substitute easily aqua ligands and interact with Pt(II) ions as a monodentate ligand in the neutral and ionic form for the ligands AMNU and MABNU, respectively. The exocyclic oxygen atoms are the most probable binding site. Square planar structures, cis-form, were proposed in both cases. The free ligands, and their Pt(II) complexes were screened for their antimicrobial activities.
Spectroscopic studies on Co(II) and Cu(II) complexes of 6-amino-1-methyl-5-nitrosouracil and its 6-methylamine derivative.[Pubmed:15477149]
Spectrochim Acta A Mol Biomol Spectrosc. 2004 Nov;60(13):3093-100.
Four complexes are obtained during the reactions of 6-Amino-1-methyl-5-nitrosouracil and its 6-methylamine derivative with Co(II) and Cu(II) ions. Theses complexes were characterized through their elemental, thermal analysis, infrared and 1H NMR spectroscopes. The obtained results indicate that, the exocyclic oxygen and nitrogen atoms are the most probable binding sites rather than ring nitrogen atoms. For cobalt complexes, the two pyrimidine bases act as bidentate ligands in the anionic form with the dissociation of iminic or N3 proton depending upon the nature of substituents on the pyrimidine ring. For copper complexes, the pyrimidine bases interact in the neutral form as monodentate ligands. Octahedral geometries are proposed for all of these complexes.
