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4-Hydroxyalternariol 9-methyl ether

CAS# 959417-17-5

4-Hydroxyalternariol 9-methyl ether

Catalog No. BCN7389----Order now to get a substantial discount!

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4-Hydroxyalternariol 9-methyl ether:5mg Please Inquire In Stock
4-Hydroxyalternariol 9-methyl ether:10mg Please Inquire In Stock
4-Hydroxyalternariol 9-methyl ether:20mg Please Inquire In Stock
4-Hydroxyalternariol 9-methyl ether:50mg Please Inquire In Stock

Quality Control of 4-Hydroxyalternariol 9-methyl ether

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Chemical structure

4-Hydroxyalternariol 9-methyl ether

3D structure

Chemical Properties of 4-Hydroxyalternariol 9-methyl ether

Cas No. 959417-17-5 SDF Download SDF
PubChem ID 24899916 Appearance Powder
Formula C15H12O6 M.Wt 288.25
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 3,4,7-trihydroxy-9-methoxy-1-methylbenzo[c]chromen-6-one
SMILES CC1=CC(=C(C2=C1C3=CC(=CC(=C3C(=O)O2)O)OC)O)O
Standard InChIKey BVYAURIYXKOUPX-UHFFFAOYSA-N
Standard InChI InChI=1S/C15H12O6/c1-6-3-10(17)13(18)14-11(6)8-4-7(20-2)5-9(16)12(8)15(19)21-14/h3-5,16-18H,1-2H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 4-Hydroxyalternariol 9-methyl ether

The liquid fermentation of Alternaria sp. Samif01.

Biological Activity of 4-Hydroxyalternariol 9-methyl ether

Description1. 4-Hydroxyalternariol 9-methyl ether shows antibacterial activity against several tested bacterial pathogens with minimum inhibitory concentration values in the range of 86.7-364.7 uM. 2. 4-Hydroxyalternariol 9-methyl ether displays promising antioxidant effects.
TargetsAntifection

4-Hydroxyalternariol 9-methyl ether Dilution Calculator

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4-Hydroxyalternariol 9-methyl ether Molarity Calculator

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Preparing Stock Solutions of 4-Hydroxyalternariol 9-methyl ether

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.4692 mL 17.3461 mL 34.6921 mL 69.3842 mL 86.7303 mL
5 mM 0.6938 mL 3.4692 mL 6.9384 mL 13.8768 mL 17.3461 mL
10 mM 0.3469 mL 1.7346 mL 3.4692 mL 6.9384 mL 8.673 mL
50 mM 0.0694 mL 0.3469 mL 0.6938 mL 1.3877 mL 1.7346 mL
100 mM 0.0347 mL 0.1735 mL 0.3469 mL 0.6938 mL 0.8673 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 4-Hydroxyalternariol 9-methyl ether

Dibenzo-alpha-pyrones from the endophytic fungus Alternaria sp. Samif01: isolation, structure elucidation, and their antibacterial and antioxidant activities.[Pubmed:27388053]

Nat Prod Res. 2017 Feb;31(4):387-396.

The EtOAc extract of the liquid fermentation of Alternaria sp. Samif01, an endophytic fungus obtained from Salvia miltiorrhiza Bunge, showed antibacterial activity against several tested bacterial pathogens. Fractionation of this extract led to the isolation of seven dibenzo-alpha-pyrones (1-7), including one new compound, 2-acetoxy-2-epi-altenuene (1) and one new natural product, 3-epi-dihydroaltenuene A (2). The structures of the new metabolites were elucidated by comprehensive analysis of the spectroscopic data including (1D, 2D) NMR and HRESIMS, while the absolute configuration of 1 was determined by TDDFT-ECD computation. Altenuisol (5), 4-hydroxyalternariol-9-methyl ether (6), and alternariol (7) showed inhibitory activities against the tested bacteria with minimum inhibitory concentration values in the range of 86.7-364.7 muM. A preliminary structure-antibacterial activity relationship was discussed. In addition, compounds 2, 5 and 6 displayed promising antioxidant effects using DPPH and hydroxyl radical assays. The cytotoxicity of the isolated compounds was evaluated as well.

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