2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acidCAS# 176983-21-4 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 176983-21-4 | SDF | Download SDF |
| PubChem ID | 637229 | Appearance | Powder |
| Formula | C30H46O5 | M.Wt | 486.69 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (1R,2R,4aS,6aR,6aS,6bR,8aR,11R,12aR,14bS)-1,11-dihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-10-oxo-3,4,5,6,6a,7,8,8a,11,12,13,14b-dodecahydro-2H-picene-4a-carboxylic acid | ||
| SMILES | CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(=O)C5(C)C)O)C)C)C2C1(C)O)C)C(=O)O | ||
| Standard InChIKey | LJORXTIGOHMBOS-OTRVPSFMSA-N | ||
| Standard InChI | InChI=1S/C30H46O5/c1-17-10-13-30(24(33)34)15-14-27(5)18(22(30)29(17,7)35)8-9-21-26(4)16-19(31)23(32)25(2,3)20(26)11-12-28(21,27)6/h8,17,19-22,31,35H,9-16H2,1-7H3,(H,33,34)/t17-,19-,20+,21-,22-,26+,27-,28-,29-,30+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The leaves of Eriobotrya japonica.
| Description | 1. 2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid has anti-HIV activity. 2. 2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid shows an inhibitory effect on the activation of Epstein-Barr virus early antigen (EBV-EA) induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) and causes a significant delay of two-stage carcinogenesis on mouse skin. |
| Targets | HIV |
2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid Dilution Calculator
2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.0547 mL | 10.2735 mL | 20.547 mL | 41.0939 mL | 51.3674 mL |
| 5 mM | 0.4109 mL | 2.0547 mL | 4.1094 mL | 8.2188 mL | 10.2735 mL |
| 10 mM | 0.2055 mL | 1.0273 mL | 2.0547 mL | 4.1094 mL | 5.1367 mL |
| 50 mM | 0.0411 mL | 0.2055 mL | 0.4109 mL | 0.8219 mL | 1.0273 mL |
| 100 mM | 0.0205 mL | 0.1027 mL | 0.2055 mL | 0.4109 mL | 0.5137 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
Featured Products
- LY 320135
Catalog No.:BCC7346
CAS No.:176977-56-3
- CCT007093
Catalog No.:BCC5147
CAS No.:176957-55-4
- Metergoline
Catalog No.:BCC6709
CAS No.:17692-51-2
- Homoplantaginin
Catalog No.:BCN2488
CAS No.:17680-84-1
- (RS)-3,4-DCPG
Catalog No.:BCC7045
CAS No.:176796-64-8
- Ageratochromene dimer
Catalog No.:BCN8110
CAS No.:17678-76-1
- Neoruscogenin
Catalog No.:BCN8168
CAS No.:17676-33-4
- trans-Hinokiresinol
Catalog No.:BCN1130
CAS No.:17676-24-3
- Phorbol
Catalog No.:BCN3726
CAS No.:17673-25-5
- KN-92
Catalog No.:BCC1680
CAS No.:176708-42-2
- Delphinidin-3,5-O-diglucoside chloride
Catalog No.:BCN1522
CAS No.:17670-06-3
- Ducheside A
Catalog No.:BCN1129
CAS No.:176665-78-4
New Products
- Ambrisentan
Catalog No.:BCC4887
CAS No.:177036-94-1
- R 568 hydrochloride
Catalog No.:BCC7781
CAS No.:177172-49-5
- 26-O-Acetylsootepin A
Catalog No.:BCN7699
CAS No.:1772588-99-4
- Aglain B
Catalog No.:BCN6636
CAS No.:177262-32-7
- DBeQ
Catalog No.:BCC3916
CAS No.:177355-84-9
- Aglain C
Catalog No.:BCN6604
CAS No.:177468-85-8
- 2-Amino-5-nitrobenzophenone
Catalog No.:BCC8537
CAS No.:1775-95-7
- Flavokawain B
Catalog No.:BCN3568
CAS No.:1775-97-9
- ZK 164015
Catalog No.:BCC7272
CAS No.:177583-70-9
- Glycerol 1-(26-hydroxyhexacosanoate)
Catalog No.:BCN1131
CAS No.:177602-14-1
- MNITMT
Catalog No.:BCC7382
CAS No.:177653-76-8
- NKP608
Catalog No.:BCC1802
CAS No.:177707-12-9
Production of bioactive triterpenes by Eriobotrya japonica calli.[Pubmed:11830140]
Phytochemistry. 2002 Feb;59(3):315-23.
Callus tissue cultures induced from an axenic leaf of Eriobotrya japonica (Rosaceae) produced triterpenes in large amounts (ca. 50 mg/g dry wt). Nine triterpenes were characterized as ursolic acid, oleanolic acid, 2alpha-hydoxyursolic acid, maslinic acid, tormentic acid, 2alpha, 19alpha-dihydroxy-3-oxo-urs-12-en-28-oic acid, hyptadienic acid and a mixture of 3-O-cis-p-coumaroyltormentic acid and 3-O-trans-p-coumaroyltormentic acid. The triterpene composition in the callus tissues was noticeably different from that in intact leaves. The contents of tormentic acid with antidiabetic action, and 2alpha, 19alpha-dihydroxy-3-oxo-urs-12-en-28-oic acid with anti-HIV activity, were much larger than those in the intact leaves. All of the triterpenes isolated from the callus tissues showed an inhibitory effect comparable to (-)-epigallocatechin gallate (EGCG) of green tea on the activation of Epstein-Barr virus early antigen (EBV-EA) induced by 12-O-tetradecanoylphorbol-13-acetate (TPA). 2alpha, 19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid was the most potent inhibitor among them and caused a significant delay of two-stage carcinogenesis on mouse skin.
2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid,176983-21-4,Natural Products, buy 2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid , 2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid supplier , purchase 2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid , 2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid cost , 2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid manufacturer , order 2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid , high purity 2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid
