1-Acetoxy-5-deacetylbaccatin ICAS# 119120-27-3 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 119120-27-3 | SDF | Download SDF |
| PubChem ID | 102004901 | Appearance | Cryst. |
| Formula | C32H44O14 | M.Wt | 652.7 |
| Type of Compound | Diterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | [(1'S,2R,2'S,3'R,5'S,7'S,8'S,9'R,10'R,13'S)-1',2',9',10',13'-pentaacetyloxy-5'-hydroxy-8',12',15',15'-tetramethylspiro[oxirane-2,4'-tricyclo[9.3.1.03,8]pentadec-11-ene]-7'-yl] acetate | ||
| SMILES | CC1=C2C(C(C3(C(CC(C4(C3C(C(C2(C)C)(CC1OC(=O)C)OC(=O)C)OC(=O)C)CO4)O)OC(=O)C)C)OC(=O)C)OC(=O)C | ||
| Standard InChIKey | YUGIEMWECOIFRK-MBMCFSISSA-N | ||
| Standard InChI | InChI=1S/C32H44O14/c1-14-21(41-15(2)33)12-32(46-20(7)38)28(45-19(6)37)26-30(10,23(42-16(3)34)11-22(39)31(26)13-40-31)27(44-18(5)36)25(43-17(4)35)24(14)29(32,8)9/h21-23,25-28,39H,11-13H2,1-10H3/t21-,22-,23-,25+,26-,27-,28-,30+,31+,32+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| In vitro | Studies on the chemical constituents of Taxus yunnanensis.[Pubmed: 1688071 ]Yao Xue Xue Bao. 1991;26(10):747-54.
|
1-Acetoxy-5-deacetylbaccatin I Dilution Calculator
1-Acetoxy-5-deacetylbaccatin I Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.5321 mL | 7.6605 mL | 15.321 mL | 30.6419 mL | 38.3024 mL |
| 5 mM | 0.3064 mL | 1.5321 mL | 3.0642 mL | 6.1284 mL | 7.6605 mL |
| 10 mM | 0.1532 mL | 0.766 mL | 1.5321 mL | 3.0642 mL | 3.8302 mL |
| 50 mM | 0.0306 mL | 0.1532 mL | 0.3064 mL | 0.6128 mL | 0.766 mL |
| 100 mM | 0.0153 mL | 0.0766 mL | 0.1532 mL | 0.3064 mL | 0.383 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Linolenic acid ethyl ester
Catalog No.:BCN8333
CAS No.:1191-41-9
- Phellolactone
Catalog No.:BCN3467
CAS No.:1190897-23-4
- Fluorobexarotene
Catalog No.:BCC6110
CAS No.:1190848-23-7
- Fmoc-Asp-OH
Catalog No.:BCC3085
CAS No.:119062-05-4
- Euchrenone B1
Catalog No.:BCN3575
CAS No.:119061-09-5
- MRT67307
Catalog No.:BCC1779
CAS No.:1190378-57-4
- EB 47
Catalog No.:BCC2452
CAS No.:1190332-25-2
- PSI-7976
Catalog No.:BCC5138
CAS No.:1190308-01-0
- PSI-7977
Catalog No.:BCC1871
CAS No.:1190307-88-0
- Sarcandrone B
Catalog No.:BCN6074
CAS No.:1190225-48-9
- Sarcandrone A
Catalog No.:BCN6073
CAS No.:1190225-47-8
- M2 ion channel blocker
Catalog No.:BCC1726
CAS No.:1190215-03-2
- IOWH-032
Catalog No.:BCC3922
CAS No.:1191252-49-9
- Ganomycin I
Catalog No.:BCN3504
CAS No.:1191255-15-8
- B-Raf inhibitor 1 dihydrochloride
Catalog No.:BCC4183
CAS No.:1191385-19-9
- 3-Oxosapriparaquinone
Catalog No.:BCN3153
CAS No.:119139-56-9
- Glychionide A
Catalog No.:BCN3250
CAS No.:119152-50-0
- Coronarin A
Catalog No.:BCN6075
CAS No.:119188-33-9
- Coronarin D
Catalog No.:BCN6076
CAS No.:119188-37-3
- Coronarin B
Catalog No.:BCN6077
CAS No.:119188-38-4
- 10-Hydroxyscandine
Catalog No.:BCN6078
CAS No.:119188-47-5
- CZC-25146
Catalog No.:BCC5371
CAS No.:1191911-26-8
- CZC 54252 hydrochloride
Catalog No.:BCC6218
CAS No.:1191911-27-9
- 4-(1H-1,2,4-Triazol-1-ylmethyl)aniline
Catalog No.:BCC8645
CAS No.:119192-10-8
[Studies on the chemical constituents of Taxus yunnanensis].[Pubmed:1688071]
Yao Xue Xue Bao. 1991;26(10):747-54.
The ethanolic extract of the bark of Taxus yunnanensis Cheng et L. K. Fu. showed significant antineoplastic effect on the transplantable tumors in mice. The life survival of P388 leukemic bearing mice was increased (84%) and the growth of B16 melanoma in mice was inhibited (53%). From this extract eight taxane diterpenoids and taxane alkaloids have been isolated. Seven of them have been identified as taxinine E(1), taxinine J(2), 1-acetoxy-5-deacetyl baccatin I(4), baccatin III(5), taxol (6), cephalomannine (7), 7-xylosyl-10-deacetyl taxol (8) from their physical and spectroscopic properties. A new taxane diterpenoid, named yunnanxane (3) was elucidated as taxa-4 (20), 11-diene-2 alpha, 5 alpha, 10 beta, 14 beta-tetraoln2 alpha,5 alpha,10 beta-triacetaten-14 beta-alpha-methyl-beta- hydroxylbutyratebyhighfield 1H NMR, 13C NMR, 1H-1HCOSY, 13C-1HCOSY, 13C-1HCOLOC and X-ray analysis. It showed the inhibitory effect on A2780 DDP, KB and HCT-8 cell line in vitro. All of the eight compounds were isolated from this species for the first time.
