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Neuroscience Research

Neuroscience is the study of the nervous system - one of the major mammalian systems responsible for sustaining life. The central nervous system (CNS) and peripheral nervous system (PNS) work in concert to coordinate basic functions such as moving and breathing, as well as 'higher order' functions including thought, speech and emotion.

Neuroscience Research Products Areas

Products for Neuroscience Research

  1. Cat.No. Product Name Activity
  2. BCC7336 A 80426 mesylate 5-HT uptake inhibitor and α 2 antagonist A 80426 mesylate
  3. BCC5033 Amitriptyline HCl 5-HT and noradrenalin re-uptake inhibitor; also TrkA/B agonist Amitriptyline HCl
  4. BCC7925 Bicifadine hydrochloride Noradrenalin, 5-HT and dopamine re-uptake inhibitor Bicifadine hydrochloride
  5. BCC5901 BTS 54-505 hydrochloride Potent SNRI; active metabolite of sibutramine BTS 54-505 hydrochloride
  6. BCC7063 Citalopram hydrobromide Highly potent and selective 5-HT uptake inhibitor Citalopram hydrobromide
  7. BCC5036 Clomipramine HCl 5-HT re-uptake inhibitor Clomipramine HCl
  8. BCC5943 Cocaine hydrochloride Inhibitor of monoamine transporters Cocaine hydrochloride
  9. BCC5064 Dapoxetine HCl Selective serotonin reuptake inhibitor Dapoxetine HCl
  10. BCC5927 Dexfenfluramine hydrochloride 5-HT re-uptake inhibitor. Also stimulates 5-HT release Dexfenfluramine hydrochloride
  11. BCC3773 Duloxetine HCl Potent 5-HT and NA reuptake inhibitor; also blocks dopamine reuptake Duloxetine HCl
  12. BCC5040 Escitalopram Oxalate Selective serotonin reuptake inhibitor (SSRI) Escitalopram Oxalate
  13. BCC1191 Fluoxetine HCl 5-HT re-uptake inhibitor Fluoxetine HCl
  14. BCC1215 Fluvoxamine maleate 5-HT re-uptake inhibitor Fluvoxamine maleate
  15. BCC7123 Indatraline hydrochloride Potent 5-HT uptake inhibitor; also inhibits dopamine and noradrenalin uptake Indatraline hydrochloride
  16. BCC7402 Lofepramine 5-HT and noradrenalin re-uptake inhibitor (SNRI) Lofepramine
  17. BCC7660 LY 393558 Dual 5-HT re-uptake inhibitor and 5-HT1B/1D antagonist LY 393558
  18. BCC7267 (±)-McN 5652 Potent, orally active 5-HT uptake inhibitor. Also inhibits noradrenalin and dopamine uptake in vitro (±)-McN 5652
  19. BCC5965 (±)-MDMA hydrochloride Inhibitor of 5-HT and dopamine uptake; hallucinogenic (±)-MDMA hydrochloride
  20. BCC6183 Mephedrone hydrochloride Inhibits synaptosomal dopamine and 5-HT uptake Mephedrone hydrochloride
  21. BCC4922 Milnacipran HCl 5-HT and noradrenalin re-uptake inhibitor (SNRI) Milnacipran HCl
  22. BCC7479 Nefazodone hydrochloride 5-HT uptake inhibitor and 5-HT2A antagonist. Antidepressant Nefazodone hydrochloride
  23. BCC7265 Paroxetine maleate Highly potent and selective 5-HT uptake inhibitor Paroxetine maleate
  24. BCC5059 Sertraline HCl 5-HT re-uptake inhibitor Sertraline HCl
  25. BCC5252 Sibutramine hydrochloride 5-HT and noradrenalin re-uptake inhibitor (SNRI) Sibutramine hydrochloride
  26. BCC5277 Tetrabenazine Potent inhibitor of vesicular monoamine transport; depletes 5-HT stores Tetrabenazine
  27. BCC2513 Venlafaxine Dual serotonin/noradrenalin re-uptake inhibitor Venlafaxine
  28. BCC6125 WY 45233 succinate Dual serotonin/noradrenalin re-uptake inhibitor WY 45233 succinate
  29. BCC7173 Zimelidine dihydrochloride Selective 5-HT uptake inhibitor Zimelidine dihydrochloride
  30. BCC4715 Serotonin HCl Endogenous substrate Serotonin HCl
  31. BCC2506 Tianeptine sodium Selective facilitator of 5-HT uptake; antidepressant Tianeptine sodium
  32. BCC6846 3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride Potent dopamine uptake inhibitor 3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride
  33. BCC6753 BTCP maleate Potent dopamine uptake inhibitor BTCP maleate
  34. BCC6845 3-CPMT Dopamine uptake inhibitor 3-CPMT
  35. BCC6676 GBR 12783 dihydrochloride Potent, selective dopamine uptake inhibitor GBR 12783 dihydrochloride
  36. BCC5129 Vanoxerine dihydrochloride Selective DA uptake inhibitor. Also σ ligand Vanoxerine dihydrochloride
  37. BCC5380 GBR 12935 dihydrochloride Selective dopamine uptake inhibitor GBR 12935 dihydrochloride
  38. BCC6640 GBR 13069 dihydrochloride Potent dopamine uptake inhibitor GBR 13069 dihydrochloride
  39. BCC7923 JHW 007 hydrochloride High affinity dopamine uptake inhibitor JHW 007 hydrochloride
  40. BCC5818 Threo-methylphenidate hydrochloride Inhibitor of dopamine and noradrenalin transporters. Psychomotor stimulant Threo-methylphenidate hydrochloride
  41. BCC7226 Nomifensine Potent noradrenalin and dopamine uptake inhibitor. Antidepressant Nomifensine
  42. BCN4960 Reserpine Inhibitor of vesicular monoamine transport Reserpine
  43. BCC7090 Rimcazole dihydrochloride DAT inhibitor. Also σ 2 antagonist Rimcazole dihydrochloride
  44. BCC1001 Adrenomedullin (1-12), human Selective fluorescent substrate of DAT and VMAT2 Adrenomedullin (1-12), human
  45. BCC6587 cis-ACBD Potent, selective L-glutamate uptake inhibitor cis-ACBD
  46. BCC6608 L-CCG-lll Potent, competitive glutamate uptake inhibitor L-CCG-lll
  47. BCC6816 Chicago Sky Blue 6B Potent inhibitor of L-glutamate uptake into synaptic vesicles; also inhibits MIF Chicago Sky Blue 6B
  48. BCC7757 7-Chlorokynurenic acid sodium salt Potent competitive inhibitor of L-glutamate uptake. Sodium salt of 7-Chlorokynurenic acid 7-Chlorokynurenic acid sodium salt
  49. BCC6577 7-Chlorokynurenic acid Potent competitive inhibitor of L-glutamate uptake 7-Chlorokynurenic acid
  50. BCC6556 Dihydrokainic acid EAAT2 (GLT-1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake Dihydrokainic acid
  51. BCC6815 Evans Blue tetrasodium salt Potent inhibitor of L-glutamate uptake into synaptic vesicles Evans Blue tetrasodium salt
  52. BCC7295 (±)-HIP-B Potent, non-competitive EAAT inhibitor (±)-HIP-B
  53. BCC6565 L-(-)-threo-3-Hydroxyaspartic acid Transportable EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor L-(-)-threo-3-Hydroxyaspartic acid
  54. BCC6804 (±)-threo-3-Methylglutamic acid EAAT2 and EAAT4 blocker (±)-threo-3-Methylglutamic acid
  55. BCC6873 MPDC Potent inhibitor of L-glutamate uptake. Less activity as a substrate compared to its parent compound, L-trans-2,4-PDC MPDC
  56. BCC6595 L-trans-2,4-PDC Transportable EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor L-trans-2,4-PDC
  57. BCC6840 SYM 2081 Inhibits EAAT2. Also kainate receptor agonist SYM 2081
  58. BCC5735 DL-TBOA Selective non-transportable inhibitor of EAATs DL-TBOA
  59. BCC5919 TFB-TBOA High affinity EAAT1 and EAAT2 blocker TFB-TBOA
  60. BCC7692 UCPH 101 Selective non-substrate EAAT1 inhibitor UCPH 101
  61. BCC7442 WAY 213613 Potent, non-substrate EAAT2 inhibitor WAY 213613
  62. BCC5896 MNI-caged-D-aspartate Caged D-aspartate; EAAT substrate MNI-caged-D-aspartate
  63. BCC2346 Begacestat γ -secretase inhibitor; lowers Aβ 40 and Aβ 42 levels Begacestat
  64. BCC2340 BMS 299897 γ -secretase inhibitor; reduces Aβ levels BMS 299897
  65. BCC7982 CEP 1347 Neuroprotective; blocks Aβ -induced cortical neuron apoptosis. Also inhibitor of JNK signaling CEP 1347
  66. BCC7667 CGP 52411 Inhibits Aβ 42 fibril formation. Also EGFR inhibitor CGP 52411
  67. BCC7363 CGP 53353 Inhibitor of de novo Aβ 42 assembly CGP 53353
  68. BCC2341 Compound W γ -secretase inhibitor; reduces Aβ 42 levels Compound W
  69. BCC3618 DAPT (GSI-IX) γ -secretase inhibitor; reduces Aβ 42 levels DAPT (GSI-IX)
  70. BCN6326 (-)-Epigallocatechin gallate Inhibits formation of amyloid fibrils (-)-Epigallocatechin gallate
  71. BCC2342 Flurizan γ -secretase inhibitor; lowers Aβ 42 levels in vitro Flurizan
  72. BCC2343 JLK 6 Inhibitor of γ -secretase-mediated β APP processing JLK 6
  73. BCC2344 L-685,458 Potent and selective γ -secretase inhibitor; inhibits Aβ 40 and Aβ 42 L-685,458
  74. BCC2345 MRK 560 γ -secretase inhibitor; attenuates amyloid plaque deposition MRK 560
  75. BCC7351 Ro 90-7501 Inhibitor of Aβ 42 fibril formation Ro 90-7501
  76. BCN5763 Tanshinone IIA Inhibits Aβ aggregation; inhibits NF-κ B and AP-1 DNA binding Tanshinone IIA
  77. BCC1044 Amyloid Beta-Peptide (12-28) (human) Amyloid β -peptide; minimum required for binding to brain proteins Amyloid Beta-Peptide (12-28) (human)
  78. BCC1045 Amyloid Beta-Peptide (1-40) (human) Amyloid β -protein fragment Amyloid Beta-Peptide (1-40) (human)
  79. BCC1027 Amyloid Beta-peptide (25-35) (human) Human amyloid β -protein fragment functionally required for neurotoxicity Amyloid Beta-peptide (25-35) (human)
  80. BCC7821 Colivelin Neuroprotective peptide; protects against β -amyloid neurotoxicity Colivelin
  81. BCC6293 CRANAD 2 Near-infrared probe that detects Aβ 40 aggregates CRANAD 2
  82. BCN5304 Cryptotanshinone Reduces Aβ generation. Also displays multiple other activities Cryptotanshinone
  83. BCC4541 Latrepirdine Neuroprotectant; protects against β -amyloid neurotoxicity Latrepirdine
  84. BCC6360 J 147 Neuroprotective and neurotrophic compound; reduces Aβ 40 and Aβ 42 levels J 147
  85. BCC5984 K 114 Amyloid fibril-specific fluorescent dye K 114
  86. BCC6113 LPYFD-NH2 Binds Aβ ; protects from aggregation induced toxicity LPYFD-NH2
  87. BCC6331 Methoxy-X04 Fluorescent amyloid β detector; brain penetrant Methoxy-X04
  88. BCC7727 Tramiprosate Targets soluble Aβ to decrease amyloid plaque deposition. Also GABA analog Tramiprosate
  89. BCC2514 Tranilast Antiallergic; binds to Aβ 40 monomers Tranilast
  90. BCC5795 Y-29794 oxalate Inhibitor of prolyl endopeptidase; prevents amyloid β -peptide-like deposition in vivo Y-29794 oxalate
  91. BCN2207 Ascorbic acid Naturally occurring antioxidant Ascorbic acid
  92. BCN5986 Celastrol Antioxidant and anti-inflammatory Celastrol
  93. BCN5954 Coenzyme Q10 Antioxidant Coenzyme Q10
  94. BCN5504 Curcumin Antitumor, anti-inflammatory and antioxidant compound Curcumin
  95. BCC4776 Dimethyl Fumarate Nrf2 pathway activator; neuroprotective Dimethyl Fumarate
  96. BCC2480 Edaravone Anti-ischemic and antioxidant Edaravone
  97. BCN5024 Fisetin Naturally occuring flavonoid and antioxidant; neuroprotective Fisetin
  98. BCC8030 L-Glutathione Reduced Endogenous antioxidant L-Glutathione Reduced
  99. BCN1001 Honokiol Antioxidant, anti-inflammatory, antitumor and antiangiogenic agent Honokiol
  100. BCC4913 Idebenone Antioxidant and neuroprotective agent Idebenone
  101. BCN5600 Luteolin Anti-inflammatory, antioxidant and free radical scavenger Luteolin

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