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Cardiovascular Research

The cardiovascular, or circulatory, system is a closed elastic circuit consisting of the heart, blood vessels (arteries, capillaries and veins) and the blood. The primary function is to pump oxygenated blood to the tissues throughout the body and reabsorb waste carbon dioxide for its removal. This function is performed by the use of pulmonary and systemic circulation.

Cardiovascular Research Products Areas

Products for Cardiovascular Research

  1. Cat.No. Product Name Activity
  2. BCC6861 Xamoterol hemifumarate β 1 selective partial agonist Xamoterol hemifumarate
  3. BCC6633 (S)-(-)-Atenolol β 1-antagonist. Active isomer of atenolol (S)-(-)-Atenolol
  4. BCC4343 Betaxolol HCl Selective β 1 antagonist Betaxolol HCl
  5. BCC4344 Bisoprolol fumarate β 1 antagonist Bisoprolol fumarate
  6. BCC6893 CGP 20712 dihydrochloride Highly potent and selective β 1 antagonist CGP 20712 dihydrochloride
  7. BCC4330 Metoprolol Tartrate Selective β 1 antagonist Metoprolol Tartrate
  8. BCC4340 Timolol Maleate β 1 antagonist Timolol Maleate
  9. BCC4349 Formoterol Hemifumarate Potent and selective β 2 agonist Formoterol Hemifumarate
  10. BCC6937 Procaterol hydrochloride Potent β 2 agonist Procaterol hydrochloride
  11. BCC4338 Salbutamol Sulfate β agonist (β 2 > β 1) Salbutamol Sulfate
  12. BCC1920 Salmeterol xinafoate Long-acting β 2 agonist; bronchodilator Salmeterol xinafoate
  13. BCC6911 Zinterol hydrochloride Selective β 2 agonist Zinterol hydrochloride
  14. BCC4029 ICI 118,551 hydrochloride Very selective β 2 antagonist/inverse agonist ICI 118,551 hydrochloride
  15. BCC6860 BRL 37344, sodium salt β 3 agonist BRL 37344, sodium salt
  16. BCC6949 CGP 12177 hydrochloride β 3 partial agonist. β 1/β 2 antagonist. CGP 12177 hydrochloride
  17. BCC7091 CL 316243 disodium salt Highly selective β 3 agonist CL 316243 disodium salt
  18. BCC5688 ICI 215,001 hydrochloride β 3 agonist ICI 215,001 hydrochloride
  19. BCC7282 L-755,507 Very potent and selective β 3 partial agonist L-755,507
  20. BCC4814 (+,-)-Octopamine HCl Invertebrate biogenic amine: activates β 3 adrenoceptors (+,-)-Octopamine HCl
  21. BCC6881 Pindolol β 3 partial agonist Pindolol
  22. BCC7833 SR 58611A hydrochloride β 3 agonist; displays anxiolytic and antidepressant effects SR 58611A hydrochloride
  23. BCC5878 ZD 2079 β 3-adrenoceptor agonist ZD 2079
  24. BCC6852 ZD 7114 hydrochloride β 3 agonist ZD 7114 hydrochloride
  25. BCC7475 L-748,337 Selective β 3 antagonist L-748,337
  26. BCC7094 SR 59230A hydrochloride Potent and selective β 3 antagonist SR 59230A hydrochloride
  27. BCC2399 Cesium chloride Inhibits the pacemaker current (If); also potassium channels blocker Cesium chloride
  28. BCC6639 YS-035 hydrochloride Inhibits pacemaker (If) current and K+ outward currents. YS-035 hydrochloride
  29. BCC7286 Zatebradine hydrochloride Blocks hyperpolarization-activated current (If) Zatebradine hydrochloride
  30. BCC6884 ZD 7288 Inhibits pacemaker (If) current ZD 7288
  31. BCC5019 Benazepril HCl Angiotensin-converting enzyme (ACE) inhibitor Benazepril HCl
  32. BCC2140 Captopril ACE inhibitor; also inhibits LTA4 hydrolase Captopril
  33. BCC5015 Moexipril HCl Angiotensin-converting enzyme (ACE) inhibitor Moexipril HCl
  34. BCC3586 Perindopril Erbumine Angiotensin-converting enzyme (ACE) inhibitor Perindopril Erbumine
  35. BCC2349 Spinorphin Enkephalin-degrading and ACE inhibitor Spinorphin
  36. BCC1004 Angiotensin I (human, mouse, rat) Endogenous peptide substrate of ACE Angiotensin I (human, mouse, rat)
  37. BCC5807 Hemopressin (rat) Bioactive substrate for endopeptidase 24.15, neurolysin and ACE Hemopressin (rat)
  38. BCC1001 Adrenomedullin (1-12), human High affinity angiotensin-converting enzyme (ACE) ligand Adrenomedullin (1-12), human
  39. BCC5018 Aliskiren Hemifumarate Potent renin inhibitor; antihypertensive Aliskiren Hemifumarate
  40. BCC3944 A 205804 Selective inhibitor of E-selectin and ICAM-1 expression A 205804
  41. BCC3946 A 286982 Potent inhibitor of the LFA-1/ICAM-1 interaction A 286982
  42. BCC5826 Ac2-12 Annexin/lipocortin 1-mimetic; inhibits leukocyte extravasation Ac2-12
  43. BCC5825 Ac2-26 Annexin/lipocortin 1-mimetic; inhibits leukocyte extravasation Ac2-26
  44. BCC3945 BIO 1211 Selective α 4β 1 (VLA-4) inhibitor BIO 1211
  45. BCC8002 BIO 5192 Highly potent and selective inhibitor of integrin α 4β 1 BIO 5192
  46. BCC3942 Cilengitide Potent and selective inhibitor of integrins α vβ 3 and α vβ 5 Cilengitide
  47. BCC5988 Echistatin, α1 isoform Integrin α Vβ 3 and glycoprotein IIb/IIIa (integrin α IIbβ 3) inhibitor Echistatin, α1 isoform
  48. BCC6998 GR 144053 trihydrochloride Glycoprotein IIb/IIIa (integrin α IIbβ 3) antagonist. Antithrombotic GR 144053 trihydrochloride
  49. BCC5938 KF 38789 Selective inhibitor of P-selectin-mediated cell adhesion KF 38789
  50. BCC6229 LDV FITC Fluorescent ligand for α 4β 1 (VLA-4) LDV FITC
  51. BCC6332 Leukadherin 1 Allosteric activator of CD11b/CD18 Leukadherin 1
  52. BCC3943 MNS Glycoprotein IIb/IIIa (α IIbβ 3) inhibitor. Also inhibits Src and Syk MNS
  53. BCC7458 OGT 2115 Heparanase inhibitor. Antiangiogenic OGT 2115
  54. BCC6275 P11 Potent antagonist of α vβ 3-vitronectin interaction; antiangiogenic P11
  55. BCC6105 PM 102 Antagonist of heparin PM 102
  56. BCC7694 RGDS peptide Integrin binding sequence; inhibits integrin receptor function RGDS peptide
  57. BCC7894 RWJ 50271 Inhibitor of LFA-1/ICAM mediated cell adhesion RWJ 50271
  58. BCC6216 TC-I 15 Potent α 2β 1 inhibitor; displays antithrombotic activity in vivo TC-I 15
  59. BCC6080 TCS 2314 α 4β 1 (VLA-4) antagonist TCS 2314
  60. BCC2471 Thiolutin Antibiotic. Inhibits vitronectin cell adhesion Thiolutin
  61. BCC5269 Acetaminophen Cyclooxygenase inhibitor; may be selective for COX-3 Acetaminophen
  62. BCC2097 Aspirin (Acetylsalicylic acid) Cyclooxygenase inhibitor; NSAID Aspirin (Acetylsalicylic acid)
  63. BCC1099 Celecoxib Selective cyclooxygenase-2 (COX-2) inhibitor Celecoxib
  64. BCC4439 Diclofenac Sodium Cyclooxygenase inhibitor; NSAID Diclofenac Sodium
  65. BCC7064 DuP 697 Cyclooxygenase-2 (COX-2) inhibitor DuP 697
  66. BCC4428 Etodolac Selective cyclooxygenase-2 (COX-2) inhibitor; NSAID Etodolac
  67. BCC1576 FK 3311 Cyclooxygenase-2 (COX-2) inhibitor FK 3311
  68. BCC3781 Flurbiprofen Cyclooxygenase inhibitor Flurbiprofen
  69. BCC7092 FR 122047 hydrochloride Cyclooxygenase (COX-1) inhibitor FR 122047 hydrochloride
  70. BCC4042 (S)-(+)-Ibuprofen Cyclooxygenase inhibitor (COX-1 > COX-2) (S)-(+)-Ibuprofen
  71. BCC3794 Indomethacin Cyclooxygenase inhibitor (COX-1 > COX-2) Indomethacin
  72. BCC6490 Naproxen Sodium Cyclooxygenase inhibitor Naproxen Sodium
  73. BCC7944 NCX 4040 NO-donating aspirin; anti-inflammatory and antitumor NCX 4040
  74. BCC6219 NCX 466 Cyclooxygenase-inhibiting nitric oxide donor NCX 466
  75. BCC6857 NS 398 Cyclooxygenase-2 (COX-2) inhibitor NS 398
  76. BCC3841 Piroxicam Cyclooxygenase-1 (COX-1) inhibitor Piroxicam
  77. BCN5607 Resveratrol Cyclooxygenase inhibitor Resveratrol
  78. BCC7111 SC 560 Cyclooxygenase-1 (COX-1) inhibitor SC 560
  79. BCC5948 SC 58125 Selective cyclooxygenase-2 (COX-2) inhibitor SC 58125
  80. BCC7809 SC 236 Selective cyclooxygenase-2 (COX-2) inhibitor SC 236
  81. BCC4861 Sulindac Cyclooxygenase inhibitor (following metabolism to sulindac sulfide) Sulindac
  82. BCC7391 Talniflumate Cyclooxygenase inhibitor. Also chloride channel blocker Talniflumate
  83. BCC7419 Tenidap NSAID, cyclooxygenase (COX-1) inhibitor. Also opener of KIR2.3 Tenidap
  84. BCC4441 Valdecoxib Selective and potent COX-2 inhibitor Valdecoxib
  85. BCC7886 BTZO 1 MIF binder BTZO 1
  86. BCC6816 Chicago Sky Blue 6B MIF inhibitor; also inhibits L-glutamate uptake into synaptic vesicles Chicago Sky Blue 6B
  87. BCC6161 (±)-CPSI 1306 Reported macrophage migration inhibitory factor (MIF) inhibitor (±)-CPSI 1306
  88. BCC5914 ER 27319 maleate Inhibits TNF-α production ER 27319 maleate
  89. BCC2096 Gabexate mesylate Inhibits TNF-α production. Also antithrombotic agent Gabexate mesylate
  90. BCC5203 VGX-1027 Immunomodulator; reduces production of pro-inflammatory cytokines VGX-1027
  91. BCC5773 10Z-Hymenialdisine Pan kinase inhibitor; blocks IL-8 production 10Z-Hymenialdisine
  92. BCC6365 iMDK Suppressor of MDK expression; inhibits PI 3-K signaling iMDK
  93. BCC6023 4-IPP Inhibitor of macrophage migration inhibitory factor (MIF); suicide substrate 4-IPP
  94. BCC5427 ISO-1 Macrophage migration inhibitory factor (MIF) inhibitor ISO-1
  95. BCC7960 (D)-(+)-Neopterin Stimulated by IFN-γ ; marker of immune activation (D)-(+)-Neopterin
  96. BCC5086 Pirfenidone Antifibrotic agent; regulates cytokine levels in vivo Pirfenidone
  97. BCC7236 SKF 86002 dihydrochloride Inhibits human monocyte IL-1 and TNF-α production; p38 MAP kinase inhibitor SKF 86002 dihydrochloride
  98. BCC4961 Suplatast Tosylate Th2 cytokine synthesis inhibitor; antiasthmatic Suplatast Tosylate
  99. BCC2248 Thalidomide TNF-α synthesis inhibitor Thalidomide
  100. BCC5812 AF 12198 Potent, selective human type I IL-1 receptor antagonist AF 12198
  101. BCC7149 YM 90709 Interleukin-5 receptor antagonist YM 90709

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