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Bay 65-1942 R form

IKKβ inhibitor, ATP-competitive and selective CAS# 758683-21-5

Bay 65-1942 R form

Catalog No. BCC1410----Order now to get a substantial discount!

Product Name & Size Price Stock
Bay 65-1942 R form:5mg $395.00 In stock
Bay 65-1942 R form:10mg $672.00 In stock
Bay 65-1942 R form:25mg $1580.00 In stock
Bay 65-1942 R form:50mg $2765.00 In stock
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Quality Control of Bay 65-1942 R form

Quality Control & MSDS

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Chemical structure

Bay 65-1942 R form

3D structure

Chemical Properties of Bay 65-1942 R form

Cas No. 758683-21-5 SDF Download SDF
PubChem ID 136091530 Appearance Powder
Formula C22H25N3O4 M.Wt 395.45
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-5-[(3R)-piperidin-3-yl]-1,4-dihydropyrido[2,3-d][1,3]oxazin-2-one
SMILES C1CC(CNC1)C2=CC(=NC3=C2COC(=O)N3)C4=C(C=CC=C4OCC5CC5)O
Standard InChIKey IGJVFGZEWDGDOO-AWEZNQCLSA-N
Standard InChI InChI=1S/C22H25N3O4/c26-18-4-1-5-19(28-11-13-6-7-13)20(18)17-9-15(14-3-2-8-23-10-14)16-12-29-22(27)25-21(16)24-17/h1,4-5,9,13-14,23,26H,2-3,6-8,10-12H2,(H,24,25,27)/t14-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of Bay 65-1942 R form

DescriptionBay 65-1942 R form is an ATP-competitive and selective inhibitor of IKKβ kinase with IC50 value of 2 nM.
TargetsIKKβ    
IC502 nM     

Bay 65-1942 R form Dilution Calculator

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Bay 65-1942 R form Molarity Calculator

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Preparing Stock Solutions of Bay 65-1942 R form

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.5288 mL 12.6438 mL 25.2876 mL 50.5753 mL 63.2191 mL
5 mM 0.5058 mL 2.5288 mL 5.0575 mL 10.1151 mL 12.6438 mL
10 mM 0.2529 mL 1.2644 mL 2.5288 mL 5.0575 mL 6.3219 mL
50 mM 0.0506 mL 0.2529 mL 0.5058 mL 1.0115 mL 1.2644 mL
100 mM 0.0253 mL 0.1264 mL 0.2529 mL 0.5058 mL 0.6322 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Background on Bay 65-1942 R form

Bay 65-1942 is an IKK-β inhibitor.

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Description

Bay 65-1942 R form is the less active R-form of Bay 65-1942. Bay 65-1942 is an ATP-competitive and selective IKKβ inhibitor.

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