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1alpha-Hydroxy VD4

CAS# 143032-85-3

1alpha-Hydroxy VD4

Catalog No. BCC1300----Order now to get a substantial discount!

Product Name & Size Price Stock
1alpha-Hydroxy VD4:1mg $781.00 In stock
1alpha-Hydroxy VD4:2mg $1328.00 In stock
1alpha-Hydroxy VD4:5mg $3124.00 In stock
1alpha-Hydroxy VD4:10mg $5467.00 In stock
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Quality Control of 1alpha-Hydroxy VD4

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Chemical structure

1alpha-Hydroxy VD4

3D structure

Chemical Properties of 1alpha-Hydroxy VD4

Cas No. 143032-85-3 SDF Download SDF
PubChem ID 9909748 Appearance Powder
Formula C28H46O2 M.Wt 414.66
Type of Compound N/A Storage Desiccate at -20°C
Synonyms 1α-Hydroxy vitamin D4
Solubility DMSO
Chemical Name (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,5S)-5,6-dimethylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
SMILES CC(C)C(C)CCC(C)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C
Standard InChIKey NEETXMRNUNEBRH-GOTXBORWSA-N
Standard InChI InChI=1S/C28H46O2/c1-18(2)19(3)9-10-20(4)25-13-14-26-22(8-7-15-28(25,26)6)11-12-23-16-24(29)17-27(30)21(23)5/h11-12,18-20,24-27,29-30H,5,7-10,13-17H2,1-4,6H3/b22-11+,23-12-/t19-,20+,24+,25+,26-,27-,28+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of 1alpha-Hydroxy VD4

Description1alpha-Hydroxy VD4 , a 1alpha(OH)D derivative, can effectively induce the differentiation of monoblastic leukaemia U937, P39/TSU and P31/FUJ cells. IC50 value; Target: VD analog

References:
[1]. M Makishima, et al. Growth inhibition and differentiation induction in human monoblastic leukaemia cells by 1alpha-hydroxyvitamin D derivatives and their enhancement by combination with hydroxyurea. British Journal of Cancer (1998) 77, 33-39

1alpha-Hydroxy VD4 Dilution Calculator

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1alpha-Hydroxy VD4 Molarity Calculator

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Preparing Stock Solutions of 1alpha-Hydroxy VD4

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.4116 mL 12.0581 mL 24.1161 mL 48.2323 mL 60.2904 mL
5 mM 0.4823 mL 2.4116 mL 4.8232 mL 9.6465 mL 12.0581 mL
10 mM 0.2412 mL 1.2058 mL 2.4116 mL 4.8232 mL 6.029 mL
50 mM 0.0482 mL 0.2412 mL 0.4823 mL 0.9646 mL 1.2058 mL
100 mM 0.0241 mL 0.1206 mL 0.2412 mL 0.4823 mL 0.6029 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Background on 1alpha-Hydroxy VD4

1alpha-Hydroxy VD4 , a 1alpha(OH)D derivative, can effectively induce the differentiation of monoblastic leukaemia U937, P39/TSU and P31/FUJ cells.

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Description

1alpha-Hydroxy VD4 , a 1alpha(OH)D derivative, can effectively induce the differentiation of monoblastic leukaemia U937, P39/TSU and P31/FUJ cells.

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