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18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one

18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one

Catalog No. BCN1494
Size Price Stock
20mg $298 In stock
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Quality Control of 18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one

Chemical structure

18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one

Biological Activity of 18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one

1. 18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one shows moderate cytotoxicity against a human lung carcinoma cell line.

18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one Dilution Calculator

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18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one Molarity Calculator

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Chemical Properties of 18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one

Cas No. 213329-46-5 SDF Download SDF
SMILES C[C@]12CCC[C@@]([C@@H]1CC(=O)c3c2ccc(c3)C(C)(C)O)(C)O
Standard InChIKey SGCHZBKQDFNHSL-BHIYHBOVSA-N
Standard InChI InChI=1S/C19H26O3/c1-17(2,21)12-6-7-14-13(10-12)15(20)11-16-18(14,3)8-5-9-19(16,4)22/h6-7,10,16,21-22H,5,8-9,11H2,1-4H3/t16-,18-,19-/m1/s1
Type of Compound Diterpenoids Appearance Powder
Formula C19H26O3 M.Wt 302.4
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.

Preparing Stock Solutions of 18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.3069 mL 16.5344 mL 33.0688 mL 66.1376 mL 82.672 mL
5 mM 0.6614 mL 3.3069 mL 6.6138 mL 13.2275 mL 16.5344 mL
10 mM 0.3307 mL 1.6534 mL 3.3069 mL 6.6138 mL 8.2672 mL
50 mM 0.0661 mL 0.3307 mL 0.6614 mL 1.3228 mL 1.6534 mL
100 mM 0.0331 mL 0.1653 mL 0.3307 mL 0.6614 mL 0.8267 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Preparation of 18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one

This product is isolated and purified from the barks of Pinus yunnanensis

References on 18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one

Diterpenoids from the buds of Pinus banksiana Lamb.[Pubmed: 22890174]


Three new diterpenoids, namely 7α-hydroxyabieta-8,11,13,15-tetraen-18-oic acid, 7β,15,18-trihydroxyabieta-8,11,13-triene, 13,15-dihydroxypodocarpa-8,11,13-triene, and 12 other known compounds were isolated from buds of Pinus banksiana Lamb. All these compounds, except for 7-oxodehydroabietinol, were isolated for the first time from this plant. Their structures were elucidated by detailed spectroscopic studies and comparison with published data. All isolated compounds were tested for cytotoxic and antibacterial activities. Overall, two compounds, 7-oxodehydroabietinol and 18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one, showed moderate cytotoxicity against a human lung carcinoma cell line.

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