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18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one

CAS# 213329-46-5

18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one

Catalog No. BCN1494----Order now to get a substantial discount!

Product Name & Size Price Stock
18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one:5mg Please Inquire In Stock
18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one:10mg Please Inquire In Stock
18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one:20mg Please Inquire In Stock
18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one:50mg Please Inquire In Stock

Quality Control of 18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one

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Chemical structure

18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one

3D structure

Chemical Properties of 18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one

Cas No. 213329-46-5 SDF Download SDF
PubChem ID 3009629 Appearance Powder
Formula C19H26O3 M.Wt 302.4
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1R,4aS,10aR)-1-hydroxy-7-(2-hydroxypropan-2-yl)-1,4a-dimethyl-3,4,10,10a-tetrahydro-2H-phenanthren-9-one
SMILES CC12CCCC(C1CC(=O)C3=C2C=CC(=C3)C(C)(C)O)(C)O
Standard InChIKey SGCHZBKQDFNHSL-BHIYHBOVSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one

The barks of Pinus yunnanensis

Biological Activity of 18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one

Description1. 18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one shows moderate cytotoxicity against a human lung carcinoma cell line.

18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one Dilution Calculator

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18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one Molarity Calculator

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Preparing Stock Solutions of 18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.3069 mL 16.5344 mL 33.0688 mL 66.1376 mL 82.672 mL
5 mM 0.6614 mL 3.3069 mL 6.6138 mL 13.2275 mL 16.5344 mL
10 mM 0.3307 mL 1.6534 mL 3.3069 mL 6.6138 mL 8.2672 mL
50 mM 0.0661 mL 0.3307 mL 0.6614 mL 1.3228 mL 1.6534 mL
100 mM 0.0331 mL 0.1653 mL 0.3307 mL 0.6614 mL 0.8267 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one

Diterpenoids from the buds of Pinus banksiana Lamb.[Pubmed:22890174]

Molecules. 2012 Aug 13;17(8):9716-27.

Three new diterpenoids, namely 7alpha-hydroxyabieta-8,11,13,15-tetraen-18-oic acid, 7beta,15,18-trihydroxyabieta-8,11,13-triene, 13,15-dihydroxypodocarpa-8,11,13-triene, and 12 other known compounds were isolated from buds of Pinus banksiana Lamb. All these compounds, except for 7-oxodehydroabietinol, were isolated for the first time from this plant. Their structures were elucidated by detailed spectroscopic studies and comparison with published data. All isolated compounds were tested for cytotoxic and antibacterial activities. Overall, two compounds, 7-oxodehydroabietinol and 18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one, showed moderate cytotoxicity against a human lung carcinoma cell line.

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