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15-Hydroxy-7-oxodehydroabietic acid

15-Hydroxy-7-oxodehydroabietic acid

Catalog No. BCN4504
Size Price Stock
20mg $298 In stock
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Quality Control of 15-Hydroxy-7-oxodehydroabietic acid

Chemical structure

15-Hydroxy-7-oxodehydroabietic acid

15-Hydroxy-7-oxodehydroabietic acid Dilution Calculator

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15-Hydroxy-7-oxodehydroabietic acid Molarity Calculator

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Chemical Properties of 15-Hydroxy-7-oxodehydroabietic acid

Cas No. 95416-25-4 SDF Download SDF
SMILES C[C@]12CCC[C@@]([C@@H]1CC(=O)c3c2ccc(c3)C(C)(C)O)(C)C(=O)O
Standard InChIKey MXPXAZNVQUWDFH-NSISKUIASA-N
Standard InChI InChI=1S/C20H26O4/c1-18(2,24)12-6-7-14-13(10-12)15(21)11-16-19(14,3)8-5-9-20(16,4)17(22)23/h6-7,10,16,24H,5,8-9,11H2,1-4H3,(H,22,23)/t16-,19-,20-/m1/s1
Type of Compound Diterpenoids Appearance Powder
Formula C20H26O4 M.Wt 330.4
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.

Preparing Stock Solutions of 15-Hydroxy-7-oxodehydroabietic acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.0266 mL 15.1332 mL 30.2663 mL 60.5327 mL 75.6659 mL
5 mM 0.6053 mL 3.0266 mL 6.0533 mL 12.1065 mL 15.1332 mL
10 mM 0.3027 mL 1.5133 mL 3.0266 mL 6.0533 mL 7.5666 mL
50 mM 0.0605 mL 0.3027 mL 0.6053 mL 1.2107 mL 1.5133 mL
100 mM 0.0303 mL 0.1513 mL 0.3027 mL 0.6053 mL 0.7567 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Preparation of 15-Hydroxy-7-oxodehydroabietic acid

This product is isolated and purified from the herbs of Pinus massoniana

References on 15-Hydroxy-7-oxodehydroabietic acid

Contact allergy to dehydroabietic acid derivatives isolated from Portuguese colophony.[Pubmed: 3191677]


7-oxodehydroabietic acid and 15-hydroxydehydroabietic acid were isolated as their methyl esters from Portuguese colophony of the gum rosin type and identified as contact allergens. Another oxidation product of dehydroabietic acid, 15-Hydroxy-7-oxodehydroabietic acid, was synthesized and identified as a component of Portuguese gum rosin. 7-oxodehydroabietic acid was found to a be a grade III allergen according to the GPMT method. Guinea pigs induced with gum rosin showed only a low response to the isolated compounds, while patients with a known allergy to gum rosin reacted to a greater extent. The results imply that the content of oxidized dehydroabietic acids in gum rosin is too low to give a marked sensitization in the animals. However, the patients might have come in contact with the allergens in technically modified rosins. The compounds showed a pattern of cross-reactivity in the animal experiments as well as among the patch tested patients.

Direct exposure electron ionization mass spectrometry and gas chromatography/mass spectrometry techniques to study organic coatings on archaeological amphorae.[Pubmed: 15739159]


DE-MS successfully identified abietanic compounds, hence a diterpenic resinous material could be identified and its degree of oxidation assessed. GC/MS enabled us to identify dehydroabietic acid, 7-oxodehydroabietic acid, 15-Hydroxy-7-oxodehydroabietic acid, 15-hydroxydehydroabietic acid, retene, tetrahydroretene, norabietatriene, norabietatetraene and methyl dehydroabietate. These oxidized and aromatized abietanes provided evidence that the amphorae examined were waterproofed with a pitch produced from resinous wood of plants from the Pinaceae family.

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