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1-Cinnamoylpyrrolidine

1-Cinnamoylpyrrolidine

Catalog No. BCN4086
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20mg $298 In stock
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Quality Control of 1-Cinnamoylpyrrolidine

Chemical structure

1-Cinnamoylpyrrolidine

1-Cinnamoylpyrrolidine Dilution Calculator

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Chemical Properties of 1-Cinnamoylpyrrolidine

Cas No. 52438-21-8 SDF Download SDF
Chemical Name (2E)-3-Phenyl-1-(1-pyrrolidinyl)-2-propen-1-one
SMILES c1ccc(cc1)/C=C/C(=O)N2CCCC2
Standard InChIKey JSIGICUAXLIURX-CMDGGOBGSA-N
Standard InChI InChI=1S/C13H15NO/c15-13(14-10-4-5-11-14)9-8-12-6-2-1-3-7-12/h1-3,6-9H,4-5,10-11H2/b9-8+
Type of Compound Alkaloids Appearance Powder
Formula C13H15NO M.Wt 201.3
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.

Preparing Stock Solutions of 1-Cinnamoylpyrrolidine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.9677 mL 24.8385 mL 49.6771 mL 99.3542 mL 124.1927 mL
5 mM 0.9935 mL 4.9677 mL 9.9354 mL 19.8708 mL 24.8385 mL
10 mM 0.4968 mL 2.4839 mL 4.9677 mL 9.9354 mL 12.4193 mL
50 mM 0.0994 mL 0.4968 mL 0.9935 mL 1.9871 mL 2.4839 mL
100 mM 0.0497 mL 0.2484 mL 0.4968 mL 0.9935 mL 1.2419 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Preparation of 1-Cinnamoylpyrrolidine

This product is isolated and purified from the herbs of Piper nigrum

References on 1-Cinnamoylpyrrolidine

Amides with anti-platelet aggregation activity from Piper taiwanense.[Pubmed: 17590283]


Three new amides, taiwanamides A-C (1-3), and two known amides, 1-cinnamoylpyrrolidine (4) and 1-(m-methoxycinnamoyl)pyrrolide (5), have been isolated from the stem of Piper taiwanense. The structures of the new amides were determined by spectral analyses. These five amides exhibited inhibitory activity of platelet aggregation in vitro. Taiwanamide C (3) owned the most potent inhibition activity of platelet aggregation induced by collagen showing IC(50) value as 8.9 microM. Taiwanamide B (2) and 1-(m-methoxycinnamoyl)pyrrolide (5) exhibited IC(50) values of 17.3 and 17.4 microM, respectively.



Phenolic acid amides: a new type of DNA strand scission agent from Piper caninum.[Pubmed: 15210155]


In a survey of the active components of crude plant extracts for their ability to cleave DNA, a crude extract prepared from Piper caninum was found to induce the relaxation of supercoiled pBR322 plasmid DNA in the presence of Cu(2+). Bioassay-guided fractionation was carried out on this extract, guided by an in vitro DNA strand scission assay. Three active principles were isolated and identified as N-cis-feruloyl tyramine (1),N-trans-feruloyl tyramine (2), and 1-cinnamoylpyrrolidine (3). Compounds 1-3 represent a structurally new type of DNA strand scission agent.



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