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Home >> Research Area >>Nature Products >> 1,5,15-Tri-O-methylmorindol


Catalog No. BCN4490
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20mg $298 In stock
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Quality Control of 1,5,15-Tri-O-methylmorindol

Chemical structure


Biological Activity of 1,5,15-Tri-O-methylmorindol

1. 1,5,15-Tri-O-methylmorindol has effects against the Epstein-Barr virus early antigen (EBV-EA) activation induced by TPA.

1,5,15-Tri-O-methylmorindol Dilution Calculator

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1,5,15-Tri-O-methylmorindol Molarity Calculator



Chemical Properties of 1,5,15-Tri-O-methylmorindol

Cas No. 942609-65-6 SDF Download SDF
SMILES COCc1ccc2c(c1OC)C(=O)c3ccc(c(c3C2=O)OC)O
Standard InChI InChI=1S/C18H16O6/c1-22-8-9-4-5-10-13(17(9)23-2)15(20)11-6-7-12(19)18(24-3)14(11)16(10)21/h4-7,19H,8H2,1-3H3
Type of Compound Anthraquinones Appearance Yellow powder
Formula C18H16O6 M.Wt 328.3
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.

Preparing Stock Solutions of 1,5,15-Tri-O-methylmorindol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.046 mL 15.23 mL 30.4599 mL 60.9199 mL 76.1499 mL
5 mM 0.6092 mL 3.046 mL 6.092 mL 12.184 mL 15.23 mL
10 mM 0.3046 mL 1.523 mL 3.046 mL 6.092 mL 7.615 mL
50 mM 0.0609 mL 0.3046 mL 0.6092 mL 1.2184 mL 1.523 mL
100 mM 0.0305 mL 0.1523 mL 0.3046 mL 0.6092 mL 0.7615 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Preparation of 1,5,15-Tri-O-methylmorindol

This product is isolated and purified from the herbs of Morinda citrifolia

References on 1,5,15-Tri-O-methylmorindol

Anti-inflammatory and potential cancer chemopreventive constituents of the fruits of Morinda citrifolia (Noni).[Pubmed: 17480098]

A new anthraquinone, 1,5,15-Tri-O-methylmorindol (1), and two new saccharide fatty acid esters, 2-O-(beta-D-glucopyranosyl)-1-O-hexanoyl-beta-D-gluropyranose (4) and 2-O-(beta-D-glucopyranosyl)-1-O-octanoyl-beta-D-gluropyranose (5), have been isolated from a methanol extract of the fruits of Morinda citrifolia (noni) along with 10 known compounds, namely, two anthraquinones (2, 3), six saccharide fatty acid esters (6-11), an iridoid glycoside (12), and a flavanol glycoside (13). Upon evaluation of six compounds (5-7, 9, 10, and 13) for inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation (1 microg/ear) in mice, four saccharide fatty acid esters, 5-7 and 9, exhibited potent anti-inflammatory activity, with ID50 values of 0.46-0.79 mg per ear. In addition, when compounds 1-13 were evaluated against the Epstein-Barr virus early antigen (EBV-EA) activation induced by TPA, all of the compounds exhibited moderate inhibitory effects (IC50 values of 386-578 mol ratio/32 pmol TPA).


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