1-(4-Hydroxyphenyl)propan-1-oneCAS# 70-70-2 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 70-70-2 | SDF | Download SDF |
| PubChem ID | 6271 | Appearance | Powder |
| Formula | C9H10O2 | M.Wt | 150.17 |
| Type of Compound | Phenylpropanoids | Storage | Desiccate at -20°C |
| Solubility | DMSO : 100 mg/mL (665.91 mM; Need ultrasonic and warming) | ||
| Chemical Name | 1-(4-hydroxyphenyl)propan-1-one | ||
| SMILES | CCC(=O)C1=CC=C(C=C1)O | ||
| Standard InChIKey | RARSHUDCJQSEFJ-UHFFFAOYSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Paroxypropione(1-(4-Hydroxyphenyl)propan-1-one) is a manufactured, nonsteroidal estrogen which has been used medically as an antigonadotropin. |
| Targets | Estrogen receptor |
| Structure Identification | Modern Chinese Medicine, 2008,10(11):13-5.Studies on the Chemical Constituents of Alpinia Calanga Willd.[Reference: WebLink]To study the chemical constituents of Alpinia galanga Willd. |
1-(4-Hydroxyphenyl)propan-1-one Dilution Calculator
1-(4-Hydroxyphenyl)propan-1-one Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 6.6591 mL | 33.2956 mL | 66.5912 mL | 133.1824 mL | 166.478 mL |
| 5 mM | 1.3318 mL | 6.6591 mL | 13.3182 mL | 26.6365 mL | 33.2956 mL |
| 10 mM | 0.6659 mL | 3.3296 mL | 6.6591 mL | 13.3182 mL | 16.6478 mL |
| 50 mM | 0.1332 mL | 0.6659 mL | 1.3318 mL | 2.6636 mL | 3.3296 mL |
| 100 mM | 0.0666 mL | 0.333 mL | 0.6659 mL | 1.3318 mL | 1.6648 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Phenolic compounds from the branches of Eucalyptus maideni.[Pubmed:22253109]
Chem Biodivers. 2012 Jan;9(1):123-30.
Three new phenolic compounds, eucalmaidin F (1), (3S)-5-guaiacyl-3-hydroxypentanoic acid (2), and 8-beta-C-glucopyranosyl-5,7-dihydroxy-2-isobutylchromone (3), were isolated from the branches of E. maideni, together with 30 known compounds, including four phenylpropanoids, three lignans, four phloroglucinol glucosides, five dihydroflavonoids, seven simple phenolic compounds, six terpenoids, and glycerol. The new structures were established by spectroscopic studies (MS, and 1D- and 2D-NMR), chemical degradation, and modified Mosher's method. Compounds 3, guaiacylglycerol, 3-hydroxy-1-(4-Hydroxyphenyl)propan-1-one, caffeic acid, (2E)-3-(4-hydroxyphenyl)prop-2-enoic acid, (7'S,8R,8'R)-lyoniresinol, (+)-lyoresinol 3alpha-O-alpha-L-rhamnopyranoside, garcimangosone, phlorocetophenone 2'-glucopyranoside, (+)-taxifolin 3alpha-O-alpha-L-rhamnopyranoside, (+)-aromadendrin, (+)-taxifolin, resveratrol, piceatannol, 3,4,5-trihydroxyphenol. Tachiaside, gallic acid, macrocapals A und G, and oleuropeic acid were evaluated for their cytotoxicities against five human cancer cell lines. Resveratrol, piceatannol, gallic acid, and macrocapal G exhibited moderate inhibitory effects on human myeloid heukemia HL-60 cell, with IC(50) values of 22.05, 22.05, 7.75, and 31.93 muM, respectively; and only macrocapal G showed inhibitory effect on hepatocellular carcinoma SMMC-7721 cell, with an IC(50) value of 26.75 muM.
Inactivation of GABA transaminase by 3-chloro-1-(4-hydroxyphenyl)propan-1-one.[Pubmed:19138517]
Bioorg Med Chem Lett. 2009 Feb 1;19(3):731-4.
Previously it was found that 4-hydroxybenzaldehyde is a competitive inhibitor of GABA transaminase. Here 3-chloro-1-(4-Hydroxyphenyl)propan-1-one (9), a 4-hydroxybenzaldehyde analogue, was found to inactivate potently the enzyme in a time-dependent manner. alpha-Ketoglutarate prevented the enzyme from inactivation, suggesting that the inactivation occurs in its active site. Several experiments indicated that the inactivation is irreversible. This study provides a novel strategy for the design of more effective inhibitors.
