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1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone

1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone

Catalog No. BCN1358
Size Price Stock
20mg $298 In stock
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Quality Control of 1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone

Chemical structure

1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone

Biological Activity of 1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone

1. 1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone has moderate cytotoxicities against breast cancer (MDA-MB-435S) and lung adenocarcinoma (A549) cell lines, but lacks antifungal activity against Candida albicans.

1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone Dilution Calculator

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Chemical Properties of 1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone

Cas No. 776325-66-7 SDF Download SDF
Chemical Name 3,4,5,8-tetrahydroxy-1,2-bis(3-methylbut-2-enyl)xanthen-9-one
SMILES CC(=CCC1=C2C(=C(C(=C1CC=C(C)C)O)O)OC3=C(C=CC(=C3C2=O)O)O)C
Standard InChIKey SHZLJVCQGYKZLS-UHFFFAOYSA-N
Standard InChI InChI=1S/C23H24O6/c1-11(2)5-7-13-14(8-6-12(3)4)19(26)21(28)23-17(13)20(27)18-15(24)9-10-16(25)22(18)29-23/h5-6,9-10,24-26,28H,7-8H2,1-4H3
Type of Compound Xanthones Appearance Yellow powder
Formula C23H24O6 M.Wt 396.4
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.

Preparing Stock Solutions of 1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.5227 mL 12.6135 mL 25.227 mL 50.4541 mL 63.0676 mL
5 mM 0.5045 mL 2.5227 mL 5.0454 mL 10.0908 mL 12.6135 mL
10 mM 0.2523 mL 1.2614 mL 2.5227 mL 5.0454 mL 6.3068 mL
50 mM 0.0505 mL 0.2523 mL 0.5045 mL 1.0091 mL 1.2614 mL
100 mM 0.0252 mL 0.1261 mL 0.2523 mL 0.5045 mL 0.6307 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Preparation of 1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone

This product is isolated and purified from the herbs of Garcinia xanthochymus

References on 1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone

Cytotoxic prenylated phenolic compounds from the twig bark of Garcinia xanthochymus.[Pubmed: 17511007]


Three new hydroxylated xanthones with prenyl or geranyl substituents, compounds 1-3, were isolated from the twig bark of Garcinia xanthochymus, along with the four known compounds 1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone (4), 1,3,5,6-tetrahydroxy-4,7,8-triprenylxanthone (5), garciniaxanthone E (6), and 6-prenylapigenin (7). Their structures were elucidated by extensive spectroscopic analysis, including 1D- and 2D-NMR as well as HR-MS experiments. All compounds showed moderate cytotoxicities against breast cancer (MDA-MB-435S) and lung adenocarcinoma (A549) cell lines, but lacked antifungal activity against Candida albicans.

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