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1,3,7-Trihydroxy-2-prenylxanthone

1,3,7-Trihydroxy-2-prenylxanthone

Catalog No. BCN4886
Size Price Stock
20mg $298 In stock
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Quality Control of 1,3,7-Trihydroxy-2-prenylxanthone

Chemical structure

1,3,7-Trihydroxy-2-prenylxanthone

Biological Activity of 1,3,7-Trihydroxy-2-prenylxanthone

1. 1,3,7-Trihydroxy-2-prenylxanthone shows weak antibacterial activity against the bacterium.

1,3,7-Trihydroxy-2-prenylxanthone Dilution Calculator

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1,3,7-Trihydroxy-2-prenylxanthone Molarity Calculator

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Chemical Properties of 1,3,7-Trihydroxy-2-prenylxanthone

Cas No. 20245-39-0 SDF Download SDF
SMILES CC(=CCc1c(cc2c(c1O)c(=O)c3cc(ccc3o2)O)O)C
Standard InChIKey FLWKTILHZPCXDW-UHFFFAOYSA-N
Standard InChI InChI=1S/C18H16O5/c1-9(2)3-5-11-13(20)8-15-16(17(11)21)18(22)12-7-10(19)4-6-14(12)23-15/h3-4,6-8,19-21H,5H2,1-2H3
Type of Compound Xanthones Appearance Yellow powder
Formula C18H16O5 M.Wt 312.3
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.

Preparing Stock Solutions of 1,3,7-Trihydroxy-2-prenylxanthone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.202 mL 16.0102 mL 32.0205 mL 64.041 mL 80.0512 mL
5 mM 0.6404 mL 3.202 mL 6.4041 mL 12.8082 mL 16.0102 mL
10 mM 0.3202 mL 1.601 mL 3.202 mL 6.4041 mL 8.0051 mL
50 mM 0.064 mL 0.3202 mL 0.6404 mL 1.2808 mL 1.601 mL
100 mM 0.032 mL 0.1601 mL 0.3202 mL 0.6404 mL 0.8005 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Preparation of 1,3,7-Trihydroxy-2-prenylxanthone

This product is isolated and purified from the fruits of Garcinia mangostana

References on 1,3,7-Trihydroxy-2-prenylxanthone

Antimicrobial activity of hydrophobic xanthones from Cudrania cochinchinensis against Bacillus subtilis and methicillin-resistant Staphylococcus aureus.[Pubmed: 17191916]


Ten xanthones with one or two isoprenoid groups and a prenylated benzophenone isolated from roots of Cudrania cochinchinensis (Moraceae) were tested for their antimicrobial activities against Bacillus subtilis and methicillin-resistant Staphylococcus aureus (MRSA). Among these compounds, gerontoxanthone H exhibited considerable antibacterial activity against B. subtilis (MIC = 1.56 microg/ml). Four xanthones, gerontoxanthone I, toxyloxanthone C, cudraxanthone S, and 1,3,7-Trihydroxy-2-prenylxanthone, showed weak antibacterial activity against the bacterium (MICs = 3.13-6.25 microg/ml). These compounds also exhibited similar MIC values against methicillin-sensitive S. aureus, MRSAs, and Micrococcus luteus.

Antimicrobial activity of isoprenoid-substituted xanthones from Cudrania cochinchinensis against vancomycin-resistant enterococci.[Pubmed: 16008130]


Ten xanthones with one or two isoprenoid groups and a prenylated benzophenone isolated from roots of Cudrania cochinchinensis (Moraceae) were tested for their antimicrobial activities against vancomycin-resistant enterococci (VRE). Among these compounds, gerontoxanthone H exhibited considerable antibacterial activity against five VRE strains (VanA, VanB and VanC) (MICs = 1.56 microg/ml). Four xanthones, 1,3,7-Trihydroxy-2-prenylxanthone, gerontoxanthone I, alvaxanthone and isoalvaxanthone, showed weaker antibacterial activity against these VREs (MICs = 3.13-6.25 microg/ml).

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