(RS)-CPPCAS# 100828-16-8 |
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Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 100828-16-8 | SDF | Download SDF |
| PubChem ID | 1228 | Appearance | Powder |
| Formula | C8H17N2O5P | M.Wt | 252.21 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble to 100 mM in water | ||
| Chemical Name | 4-(3-phosphonopropyl)piperazine-2-carboxylic acid | ||
| SMILES | C1CN(CC(N1)C(=O)O)CCCP(=O)(O)O | ||
| Standard InChIKey | CUVGUPIVTLGRGI-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C8H17N2O5P/c11-8(12)7-6-10(4-2-9-7)3-1-5-16(13,14)15/h7,9H,1-6H2,(H,11,12)(H2,13,14,15) | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Potent NMDA antagonist. Separate isomer (R)-CPP also available. |
(RS)-CPP Dilution Calculator
(RS)-CPP Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.9649 mL | 19.8247 mL | 39.6495 mL | 79.299 mL | 99.1237 mL |
| 5 mM | 0.793 mL | 3.9649 mL | 7.9299 mL | 15.8598 mL | 19.8247 mL |
| 10 mM | 0.3965 mL | 1.9825 mL | 3.9649 mL | 7.9299 mL | 9.9124 mL |
| 50 mM | 0.0793 mL | 0.3965 mL | 0.793 mL | 1.586 mL | 1.9825 mL |
| 100 mM | 0.0396 mL | 0.1982 mL | 0.3965 mL | 0.793 mL | 0.9912 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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CPP, a new potent and selective NMDA antagonist. Depression of central neuron responses, affinity for [3H]D-AP5 binding sites on brain membranes and anticonvulsant activity.[Pubmed:2876749]
Brain Res. 1986 Sep 10;382(1):169-73.
Properties of a new potent antagonist acting selectively at N-methyl-D-aspartate (NMDA) type excitatory amino acid receptors are described. This compound, 3-((+/-)-2-carboxypiperazin-4-yl)propyl-1-phosphonic acid (CPP) is more potent than all previously reported NMDA antagonists in depressing mammalian spinal neuronal responses (cat and immature rat), in its affinity for [3H]D-AP5 (a radiolabelled NMDA antagonist) binding sites on rat brain membranes, and as an anticonvulsant in mice.
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