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(RS)-3-Hydroxyphenylglycine

(RS)-3-Hydroxyphenylglycine

Catalog No. BCC6604
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10mg $153.00 Ship Within 7 Days
50mg $644.00 Ship Within 7 Days
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Quality Control of (RS)-3-Hydroxyphenylglycine

Chemical structure

(RS)-3-Hydroxyphenylglycine

Biological Activity of (RS)-3-Hydroxyphenylglycine

Agonist at PI-linked metabotropic glutamate receptors. Separate isomer (S)-3-Hydroxyphenylglycine also available.

(RS)-3-Hydroxyphenylglycine Dilution Calculator

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(RS)-3-Hydroxyphenylglycine Molarity Calculator

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Chemical Properties of (RS)-3-Hydroxyphenylglycine

Cas No. 31932-87-3 SDF Download SDF
Synonyms (RS)-3H-PG
Chemical Name 2-amino-2-(3-hydroxyphenyl)acetic acid
SMILES C1=CC(=CC(=C1)O)C(C(=O)O)N
Standard InChIKey DQLYTFPAEVJTFM-UHFFFAOYSA-N
Standard InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)
Formula C8H9NO3 M.Wt 167.16
Solubility Soluble to 100 mM in 1eq. NaOH
Storage Desiccate at RT
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.

Preparing Stock Solutions of (RS)-3-Hydroxyphenylglycine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.9823 mL 29.9115 mL 59.8229 mL 119.6458 mL 149.5573 mL
5 mM 1.1965 mL 5.9823 mL 11.9646 mL 23.9292 mL 29.9115 mL
10 mM 0.5982 mL 2.9911 mL 5.9823 mL 11.9646 mL 14.9557 mL
50 mM 0.1196 mL 0.5982 mL 1.1965 mL 2.3929 mL 2.9911 mL
100 mM 0.0598 mL 0.2991 mL 0.5982 mL 1.1965 mL 1.4956 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

References on (RS)-3-Hydroxyphenylglycine

4C3HPG (RS-4-carboxy-3-hydroxyphenylglycine), a weak agonist at metabotropic glutamate receptors, occludes the action of trans-ACPD in hippocampus.[Pubmed: 1385184]


The determination of the physiological role of glutamatergic metabotropic actions has been hampered by the lack of potent and specific antagonists. It has recently been reported that 4C3HPG (RS-4-carboxy-3-hydroxyphenylglycine) can antagonize metabotropic responses in the central nervous system. The effects of 4C3HPG on metabotropic responses evoked by trans-ACPD were investigated in CA3 pyramidal cells in hippocampal slice cultures. Our results show that in hippocampus 4C3HPG fails to antagonize responses mediated by metabotropic glutamate receptors.

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