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[Phe8Ψ(CH-NH)-Arg9]-Bradykinin

[Phe8Ψ(CH-NH)-Arg9]-Bradykinin

Catalog No. BCC5995
Size Price Stock
1mg $226.00 Ship Within 7 Days
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Quality Control of [Phe8Ψ(CH-NH)-Arg9]-Bradykinin

Chemical structure

[Phe8Ψ(CH-NH)-Arg9]-Bradykinin

Biological Activity of [Phe8Ψ(CH-NH)-Arg9]-Bradykinin

Selective bradykinin B2 receptor agonist that is resistant to carboxypeptidase cleavage. 5-fold more potent and exhibits a more prolonged duration of action than bradykinin (Cat No. 3004) in vivo.

[Phe8Ψ(CH-NH)-Arg9]-Bradykinin Dilution Calculator

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[Phe8Ψ(CH-NH)-Arg9]-Bradykinin Molarity Calculator

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Chemical Properties of [Phe8Ψ(CH-NH)-Arg9]-Bradykinin

Cas No. 118122-39-7 SDF Download SDF
Sequence RPPGFSPFR

(Modifications: Phe-8 - Arg-9 peptide bond replaced with Ψ-(CH2-NH))

Chemical Name (2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropyl]amino]-5-(diaminomethylideneamino)pentanoic acid
SMILES N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N2CCC[C@H]2C(=O)NCC(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](CO)C(=O)N4CCC[C@H]4C(=O)N[C@H](CN[C@@H](CCCN=C(N)N)C(O)=O)Cc5ccccc5 N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N2CCC[C@H]2C(=O)NCC(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](CO)C(=O)N4CCC[C@H]4C(=O)N[C@H](CN[C@@H](CCCNC(N)=N)C(O)=O)Cc5ccccc5
Standard InChIKey XKJBISGEHGXKBF-TZPCGENMSA-N
Standard InChI InChI=1S/C50H75N15O10/c51-34(16-7-21-56-49(52)53)45(71)65-25-11-20-40(65)47(73)64-24-9-18-38(64)43(69)59-29-41(67)61-36(27-32-14-5-2-6-15-32)42(68)62-37(30-66)46(72)63-23-10-19-39(63)44(70)60-33(26-31-12-3-1-4-13-31)28-58-35(48(74)75)17-8-22-57-50(54)55/h1-6,12-15,33-40,58,66H,7-11,16-30,51H2,(H,59,69)(H,60,70)(H,61,67)(H,62,68)(H,74,75)(H4,52,53,56)(H4,54,55,57)/t33-,34-,35-,36-,37-,38-,39-,40-/m0/s1
Formula C50H75N15O10 M.Wt 1046.23
Solubility Soluble to 1 mg/ml in water
Storage Desiccate at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.

Preparing Stock Solutions of [Phe8Ψ(CH-NH)-Arg9]-Bradykinin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 0.9558 mL 4.7791 mL 9.5581 mL 19.1163 mL 23.8953 mL
5 mM 0.1912 mL 0.9558 mL 1.9116 mL 3.8233 mL 4.7791 mL
10 mM 0.0956 mL 0.4779 mL 0.9558 mL 1.9116 mL 2.3895 mL
50 mM 0.0191 mL 0.0956 mL 0.1912 mL 0.3823 mL 0.4779 mL
100 mM 0.0096 mL 0.0478 mL 0.0956 mL 0.1912 mL 0.239 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Kewords:

[Phe8Ψ(CH-NH)-Arg9]-Bradykinin,118122-39-7,GPCR/G protein,Bradykinin Receptors, supplier, inhibitor,Antagonist,Blocker,Modulator,Agonist, activators, activates, potent, BioCrick

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