Search Site
Home >> Research Area >>GPCR/G protein>>NOP Receptor >> [Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2
[Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2

[Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2

Catalog No. BCC5701
Size Price Stock
1mg $347.00 Ship Within 7 Days
Related Products

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris

Quality Control of [Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2

Chemical structure

[Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2

[Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2 Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

[Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2 Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Chemical Properties of [Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2

Cas No. 213130-17-7 SDF Download SDF
Sequence FGGFTGARKSARK

(Modifications: Phe-1 - Gly-2 peptide bond replace with Psi-(CH2-NH), Lys-13 = C-terminal amide)

Formula C61H102N22O14 M.Wt 1367.6
Solubility Soluble to 0.70 mg/ml in water
Storage Desiccate at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.

Preparing Stock Solutions of [Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 0.7312 mL 3.656 mL 7.3121 mL 14.6242 mL 18.2802 mL
5 mM 0.1462 mL 0.7312 mL 1.4624 mL 2.9248 mL 3.656 mL
10 mM 0.0731 mL 0.3656 mL 0.7312 mL 1.4624 mL 1.828 mL
50 mM 0.0146 mL 0.0731 mL 0.1462 mL 0.2925 mL 0.3656 mL
100 mM 0.0073 mL 0.0366 mL 0.0731 mL 0.1462 mL 0.1828 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

References on [Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2

Evidence that [Phe1 psi(CH2-NH)Gly2]nociceptin-(1-13)-NH2, a peripheral ORL-1 receptor antagonist, acts as an agonist in the rat spinal cord.[Pubmed: 9846631]


[Phe1 psi(CH2-NH)Gly2]nociceptin-(1-13)-NH2, a pseudopeptide analogue of nociceptin is an antagonist in peripheral assays. Here, using in vivo electrophysiological recordings of dorsal horn neurones, [Phe1 psi(CH2-NH)Gly2]nociceptin-(1-13)-NH2 appears to have agonist activity after spinal administration. The noxious evoked activity of the neurones was inhibited by [Phe1 psi(CH2-NH)Gly2]nociceptin-(1-13)-NH2, which was as potent as nociceptin itself.

Kewords:

[Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2,213130-17-7,GPCR/G protein,NOP Receptor, supplier, inhibitor,Antagonist,Blocker,Modulator,Agonist, activators, activates, potent, BioCrick

Online Inquiry

Fill out the information below

* Required Fields

CheckCode: